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Room-temperature phosphorimetry of methylxanthine stimulants on zeolite-modified filter paper substrates

  • Original Papers
  • Pharmaceutical Analysis
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Summary

The phosphorescence characteristics at room temperature of methylxanthine stimulants (caffeine, theophylline and theobromine) on several filter paper substrates (Whatman #1, Whatman DE-81 and Albet) modified with a cation-exchange zeolite have been studied. The zeolite was incorporated into the paper matrix by immersion and stirring of the filter paper in a zeolite aqueous suspension. The effect of zeolite on the phosphorescence decay of the drugs has been studied. Compared to the untreated filter papers, the zeolite-modified paper substrate shows lower background signal and enhanced analyte phosphorescence. As a result, improved limits of detection are found under optimum experimental conditions.

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References

  1. Vo-Dinh T (1984) Room Temperature Phosphorimetry for Chemical Analysis. Wiley, New York

    Google Scholar 

  2. Hurtubise RJ (1990) Phosphorimetry: Theory, Instrumentation and Applications, VCH, New York

    Google Scholar 

  3. Schulman EM, Walling C (1973) J Phys Chem 77:902

    Google Scholar 

  4. Parker RT, Freedlander RS, Dunlap R (1980) Anal Chim Acta 119:189

    Google Scholar 

  5. Bateh RP, Winefordner JD (1982) Talanta 29:713

    Google Scholar 

  6. Ramis Ramos G, Garcia Alvarez-Coque MC, O'Reilly AM, Khasawneh IM, Winefordner JD (1988) Anal Chem 60:416

    Google Scholar 

  7. De Lima CG, Andino MM, Winefordner JD (1986) Anal Chem 58:2867

    Google Scholar 

  8. Aaron JJ, Campligia AD, Winefordner JD (1990) Anal Chim Acta 236:257

    Google Scholar 

  9. Alak M, Vo-Dinh T (1988) Anal Chem 60:596

    Google Scholar 

  10. Campligia AD, De Lima CG (1987) Anal Chem 59:2827

    Google Scholar 

  11. Gaye MD, Aaron JJ (1989) Talanta 36:445

    Google Scholar 

  12. Cabalin LM, Ruperez A, Laserna JJ (1992) Anal Chim Acta 270:239

    Google Scholar 

  13. Campligia AD, Laserna JJ, Berthod A, Winefordner JD (1991) Anal Chim Acta 244:215

    Google Scholar 

  14. Smith JV (1963) Mineralogical Society of America, Special paper 1

  15. Suib SL, Galen Stucky D (1980) J of Catalysis 65:179

    Google Scholar 

  16. Ruperez A, Ayala L, Laserna JJ (1990) Appl Spectrosc 44:465

    Google Scholar 

  17. Ruperez A, Ayala L, Laserna JJ (1990) Talanta 37:859

    Google Scholar 

  18. Ruperez A, Ayala L, Laserna JJ (1992) Spectrochim Acta 48A:569

    Google Scholar 

  19. Cline Love LJ, Upton LM (1980) Anal Chem 52:496

    Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Analytical Chemistry, Faculty of Sciences, University of Málaga, E-29071, Málaga, Spain

    L. M. Cabalin & J. J. Laserna

  2. Department of Physical Chemistry, Faculty of Sciences, University of Málaga, E-29071, Málaga, Spain

    A. Ruperez

Authors
  1. L. M. Cabalin
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  2. J. J. Laserna
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  3. A. Ruperez
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Cabalin, L.M., Laserna, J.J. & Ruperez, A. Room-temperature phosphorimetry of methylxanthine stimulants on zeolite-modified filter paper substrates. Fresenius J Anal Chem 346, 1003–1007 (1993). https://doi.org/10.1007/BF00322767

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  • DOI: https://doi.org/10.1007/BF00322767

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