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Development of retinofugal neuropil areas in the brain of the alpine newt, Triturus alpestris

II. Topographic organization and formation of projections

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Summary

The development of retinal projections and the formation of their retinotopic organization were studied by means of anterograde transport of horseradish peroxidase in the newt, Triturus alpestris. All tracts found in the adult on the contralateral brain side are established during embryonic stages. At this stage a few uncrossed fibers are also detectable. Retinal fibers project first to the contralateral optic tectum. These are followd by contralateral projections to thalamic recipient areas. Beginning at embryonic stages, the projections from the retinal quadrants into the optic tectum are topographically organized. The other terminal areas innervated by the marginal optic tract (MaOT) show a topographic order from midlarval stages. The terminal areas innervated by the medial optic tract (MeOT) show no clear topographic organization at any stage. The contralateral projection of the MeOT orginates from the central area of the retina, whereas the uncrossed projection originates from the temporal peripheral retina. Ipsilateral (uncrossed) retinal projections develop during metamorphic climax. The MeOT is more distinct than the MaOT. The latter shows a clear retinotopic organization. The topography of the ipsilateral MaOT and its corresponding terminal areas are mirror-symmetric to the contralateral tract and terminal areas.

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Abbreviations

AOF :

Axial optic fascicle

BON :

Basal optic neuropil

BOT :

Basal optic tract

c :

Caudal

C :

CGT, corpus geniculatum thalamicum

d :

Dorsal

dg :

Dorsal retinal quadrant

m :

Medial

MgOT :

Marginal optic tract

Med :

Medulla oblongata

MeOT :

Medial optic tract

NBl :

Neuropil Bellonci pars lateralis

NBm :

Neuropil Bellonci pars medialis

ON :

Optic nerve

nq :

Nasal retinal quadrant

OT :

Optic tract

PTN, P :

Posterior thalamic neuropil

r :

Rostral

t :

Temporal

Tel :

Telencephalon

TO :

Optic tecrum

tq :

Temporal retinal quadrant

UF, U :

Uncinate field

v :

Ventral

vq :

Ventral retinal quadrant

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  1. Institut für Zoologie, Technische Hochschule Darmstadt, Institut für Zoologie, Schnittspahnstraße 3, D-6100, Darmstadt, Federal Republic of Germany

    Georg Rettig

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Rettig, G. Development of retinofugal neuropil areas in the brain of the alpine newt, Triturus alpestris . Anat Embryol 177, 257–265 (1988). https://doi.org/10.1007/BF00321136

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