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The fine structure of the caudal neurosecretory system in Raia batis

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Summary

The fine structure of the caudal neurosecretory system in Raia batis was studied. Far-reaching similarities with ultrastructural details of other vertebrate neurosecretory systems were noted. The secretion is present in all parts of the system in the form of elementary neurosecretory granules which seem to be formed in the Golgi complex of the cell body. The morphology of the terminal region is discussed in relation to the possible mode of secretion release and in connection with the routes of secretion to the vascular lumen.

The Dahlgren cell is not considered to be a secretory neuron, but a specialized glandular cell type, which has, to some extent, the same properties as nerve cells.

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References

  • Afzelius, B. A.: The ultrastructure of the nuclear membrane of the sea urchin oocyte as studied with the electron microscope. Exp. Cell Res. 8, 147–158 (1955).

    Google Scholar 

  • —: Electron microscopy of Golgi elements in sea urchin eggs. Exp. Cell Res. 11, 67–85 (1956).

    Google Scholar 

  • Bargmann, W.: Elektronenmikroskopische Untersuchungen an der Neurohypophyse. Zweites Int. Symposium über Neurosekretion, S. 4–12. Berlin-Göttingen-Heidelberg: Springer 1958.

    Google Scholar 

  • Bargmann u. A. Knoop: Über die morphologischen Beziehungen des neurosekretorischen Zwischenhirnsystems zum Zwischenlappen der Hypophyse (licht-und elektronenmikroskopische Untersuchungen). Z. Zellforsch. 52, 256–277 (1960).

    Google Scholar 

  • — u. A. Thiel: Elektronenmikroskopische Studien an der Neurohypophyse von Tropidonotus natrix. Z. Zellforsch. 47, 114–126 (1957).

    Google Scholar 

  • Bennett, M. V. L., and S. Fox: Electrophysiology of caudal neurosecretory cells in the skate and fluke. Gen. comp. Endocr. 2 (1), 77–95 (1962).

    Google Scholar 

  • Bern, H. A.: The properties of neurosecretory cells. Gen. comp. Endocr., Suppl. 1, 117–132 (1962).

    Google Scholar 

  • —, and I. R. Hagadorn: Urohypophysis of fishes. A comment on the elasmobranch caudal neurosecretory system. In: Symposium on Comparative Endocrinology held at Cold Spring Harbor, 1958 (Ed. A. Gorbman), pp. 725–727. New York: J. Wiley and Sons Inc. 1959.

    Google Scholar 

  • —, R. S. Nishioka and I. R. Hagadorn: Association of elementary neurosecretory granules with the Golgi complex. J. Ultrastruct. Res. 5, 311–320 (1961).

    Google Scholar 

  • —, and N. Takasugi: The caudal neurosecretory system of fishes. Gen. comp. Endocr. 2, 96–110 (1962).

    Google Scholar 

  • Bloom, G., E. Östlund, U. S. v. Euler, F. Lishasko, M. Ritzen and J. Adams-Ray: Studies on catecholamine-containing granules of specific cells in cyclostome hearts. Acta physiol. scand. 53, Suppl. 185, 1–34 (1961).

    Google Scholar 

  • Boycott, B. B., E. G. Gray and R. W. Guillery: Synaptic structure and its alteration with environmental temperature: a study by light and electron microscopy of the central nervous system. Proc. roy. Soc. B 154, 151–172 (1961).

    Google Scholar 

  • Breemen, V. L. van, E. Anderson and J. F. Reger: An attempt to determine the origin of synaptic vesicles. Exp. Cell Res., Suppl. 5, 153–167 (1958).

    Google Scholar 

  • Chou, J. T. Y., and G. A. Meek: The Ultra-fine structure of lipid globules in the neurones of Helix aspersa. Quart. J. micr. Sci. 99, 279–284 (1958).

    Google Scholar 

  • Dalton, A. J.: Morphology and physiology of the Golgi apparatus. Cell. physiol. of neoplasia, pp. 161–184. Austin: Univ. of Texas Press 1960.

    Google Scholar 

  • Duncan, D.: Electron microscopy of the hypophysis, pars neuralis. Anat. Rec. 121, 430 (1955).

    Google Scholar 

  • —: An electron microscope study of the neurohypophysis of a bird, Gallus domesticus. Anat. Rec. 125, 457–473 (1956).

    Google Scholar 

  • —, and R. Alexander: An electron microscope study of the supraoptic nucleus of the rat. Anat. Rec. 139, 223 (1961).

    Google Scholar 

  • Edwards, G. A., H. Ruska and D. E. Harven: Electronmicroscopy of peripheral nerves and neuromuscular junctions in the wasp legs. J. biophys. biochem. Cytol. 4, 107–114 (1958).

    Google Scholar 

  • Elbers, P. F.: An improved grid-holder for the Siemens electron microscope. J. biophys. biochem. Cytol. 16, 114–115 (1959).

    Google Scholar 

  • Enami, M.: Studies in neurosecretion. II. Caudal neurosecretory system in the eel (Anguilla japonica). Gunma J. med. Sci. 4, 23–36 (1955).

    Google Scholar 

  • —: The morphology and functional significance of the caudal neurosecretory system of fishes. In: Symposium on Comparative Endocrinology held at Cold Spring Harbor, 1958 (Ed. A. Gorbman), pp. 697–724. New York: J. Wiley and Sons Inc. 1959.

    Google Scholar 

  • —, and K. Imai: Studies on neurosecretion XII. Electron microscopy of the secrete granules in the caudal neurosecretory system of the eel. Proc. Jap. Acad. 34, 164–168 (1958).

    Google Scholar 

  • Fingerman, M., and T. Aoto: Electron microscopy of neuro-secretory cells and their products in the dwarf crayfish, Cambarellus shufeldti. Anat. Rec. 131 (3), 552 (1958).

    Google Scholar 

  • Fridberg, G.: A histological evidence of the homology between Dahlgren's cells in rays and teleosts. Acta zool. (Stockh.) 40, 1–4 (1959).

    Google Scholar 

  • —: Studies on the caudal neurosecretory system in teleosts. Acta zool. (Stockh.) 43, 1–77 (1962).

    Google Scholar 

  • —: The caudal neurosecretory system in some elasmobranchs. Gen. comp. Endocr. 2, 249–265 (1962).

    Google Scholar 

  • Fujita, H., and J. F. Hartmann: Electron microscopy of neurohypophysis in normal, adrenalin-treated and pilocarpine-treated rabbits. Z. Zellforsch. 54, 734–763 (1961).

    Google Scholar 

  • Gerschenfeld, H. M., J. H. Tramezzani and E. de Robertis: Ultrastructure and function in neurohypophysis of the toad. Endocrinology 66, (5) 741–762 (1960).

    Google Scholar 

  • Gray, E. G.: Electron microscopy of dendrites and axons of the cerebral cortex. J. Physiol. (Lond.) 145, 25–26 (1959).

    Google Scholar 

  • —, and V. P. Whittaker: The isolation of synaptic vesicles from the central nervous system. J. Physiol. (Lond.) 153, 35P-37P (1960).

    Google Scholar 

  • Green, J. D., and V. L. van Breemen: Electron microscopy of the pituitary and observations on neurosecretion. Amer. J. Anat. 97 (4), 177–203 (1955).

    Google Scholar 

  • —, and D. S. Maxwell: Comparative anatomy of the hypophysis and observations on the mechanism of neurosecretion. In: Symposium on Comparative Endocrinology held at Cold Spring Harbor, 1958, (Ed. A. Gorbman) pp. 368–392. New York: J. Wiley and Sons Inc. 1959.

    Google Scholar 

  • Hager, H., and W. L. Tafuri: Elektronenoptischer Nachweis sog. neurosekretorischer Elementargranula in marklosen Nervenfasern des Plexus myentericus (Auerbach) des Meerschweinchens. Naturwissenschaften 46, 333–334 (1959).

    Google Scholar 

  • Hartmann, J. F.: Electron microscopy of the neurohypophysis in normal and histamine treated rats. Z. Zellforsch. 48, 291–308 (1958).

    Google Scholar 

  • Holmes, R. L., and F. G. M. Knowles: ‘Synaptic vesicles’ in the neurohypophysis. Nature (Lond.) 185 (4714), 711–712 (1960).

    Google Scholar 

  • Holmgren, U.: On the caudal neurosecretory system of the eel. Anat. Rec. 135, 1, 51–59 (1959).

    Google Scholar 

  • — and G. B. Chapman: The fine structure of urophysis spinalis of the teleost fish, Fundulus heteroclitus L. J. Ultrastruct. Res. 4, 15–25 (1960).

    Google Scholar 

  • Ishibashi, T.: Electrical activity of the caudal neurosecretory cells in the eel (Anguilla japonica) with special reference to synaptic transmission. Gen. comp. Endocr. 2, 415–424 (1962).

    Google Scholar 

  • Katz, B.: The transmission of impulses from nerve to muscle, and the subcellular unit of synaptic action. Proc. roy. Soc. B 155, 455–477 (1962).

    Google Scholar 

  • Koelle, G. B.: A proposed dual neurohumoral role of acetylcholine: its functions of the pre- and post-synaptic sites. Nature (Lond.) 190 (4772), 208–211 (1961).

    Google Scholar 

  • Kurosumi, K.: Electron microscopic analysis of the secretion mechanism. Int. Rev. Cytol. 11, 1–117 (1961).

    Google Scholar 

  • Legait, E., et H. Legait: Etude de l'hypophyse de quelques teleostéens au microscope électronique. Arch. anat. (Strasbourg) 41, 5–35 (1958).

    Google Scholar 

  • Luft, J. H.: Improvements in epoxy resin embedding method. J. biophys. biochem. Cytol. 9, 409–414 (1961).

    Google Scholar 

  • Morita, H., T. Ishibashi and S. Yamashita: Synaptic transmission in neurosecretory cells. Nature (Lond.) 191 (4784), 183 (1961).

    Google Scholar 

  • Murakami, M.: Elektronenmikroskopische Untersuchung der neurosekretorischen Zellen im Hypothalamus der Maus. Z. Zellforsch. 56, 277–299 (1962).

    Google Scholar 

  • Nakajima, J.: Electron microscope observations on the nerve fibres of Christaria plicata. Z. Zellforsch. 54, 261–274 (1961).

    Google Scholar 

  • Nass, M. M. K., and S. Nass: Fibrous structures within the matrix of developing chick embryo mitochondria. Exp. Cell Res. 26, 424–427 (1962).

    Google Scholar 

  • Nishiitsutsutji-Uwo J.: Electron microscopic studies on the neurosecretory system in Lepidoptera. Z. Zellforsch. 54, 613–630 (1961).

    Google Scholar 

  • Palade, G. E.: Fine structure of blood capillaries. J. appl. Physics 24, 1424 (1953).

    Google Scholar 

  • —: The endoplasmic reticulum. J. biophys. biochem. Cytol. 2 Suppl., 84–98 (1956).

    Google Scholar 

  • —, and P. Siekevitz: Liver microsomes. An integrated morphological and biochemical study. J. biophys. biochem. Cytol. 2, 171–200 (1956).

    Google Scholar 

  • Palay, S. L.: An electron microscope study of the neurohypophysis in normal, hydrated, and dehydrated rats. Anat. Rec. 121, 348 (1955).

    Google Scholar 

  • —: Structure and function in the neuron. Progress in neurobiology. I. Neurochemistry (Ed. S. Korey and S. I. Nurnberger, pp. 64–82. New York: Hoeber 1956.

    Google Scholar 

  • —: Synapses in the central nervous system. J. biophys. biochem. Cytol. 2 Suppl., 193–202 (1956).

    Google Scholar 

  • —: The fine structure of the neurohypophysis. Progress in neurobiology. II. Ultrastructure and cellular chemistry of neural tissue (Ed. S. Korey and J. I. Nurnberger), pp. 31–49. New York: Hoeber 1957.

    Google Scholar 

  • Palay, S. L.: The morphology of secretion. In: Frontiers in cytology (Ed. S. L. Palay), pp. 305–342. New Haven: Yale Univ. Press 1958.

    Google Scholar 

  • —: The fine structure of neurosecretory neurons in the praeoptic nucleus of the goldfish (Carassius auratus). Anat. Rec. 138, 417–443 (1960).

    Google Scholar 

  • —:, and G. E. Palade: The fine structure of neurons. J. biophys. biochem. Cytol. 1, 69–88 (1955).

    Google Scholar 

  • Palmgren, A.: Specific silver staining of nerve fibres. I. Technique for vertebrates. Acta zool. (Stockh.) 41, 239–265 (1960).

    Google Scholar 

  • Pappas, G. D.: Transport of colloidal particles across the corneal endothelium. Proc. 5th Internat. Congr. Electr. Micr. Philadelphia II. cc-2 (1962).

  • Pease, D. C.: The basement membrane: substratum of histological order and complexity. Vierter Internat. Kongr. für Elektronenmikroskopie, Berlin 1958, II, S. 139–155 (1958).

    Google Scholar 

  • Potter, D. D., and W. R. Loewenstein: Electrical activity of neurosecretory cells. Amer. J. Physiol. 183, 652 (1955).

    Google Scholar 

  • Robertis, E. De: Submicroscopic morphology of the synapse. Int. Rev. Cytol. 8, 61–94 (1959).

    Google Scholar 

  • —, and A. De Iraldi: Plurivesicular secretory processes and nerve endings in the pineal gland of the rat. J. biophys. biochem. Cytol. 10, (3) 361–372 (1961).

    Google Scholar 

  • Sano, Y.: Über die Neurophysis (sog. Kaudalhypophyse, „Urohypophyse“) des Teleostiers Tinea vulgaris. Z. Zellforsch. 47, 481–497 (1958).

    Google Scholar 

  • —: Das caudale neurosekretorische System bei Fischen. Ergebn. Biol. 24, 191–212 (1961).

    Google Scholar 

  • —, and A. Knoop: Elektronenmikroskopische Untersuchungen am kaudalen neurosekretorischen System von Tinea vulgaris. Z. Zellforsch. 49, 464–492 (1959).

    Google Scholar 

  • Scharrer, E., and S. Brown: Neurosecretion. XII. The formation of neurosecretory granules in the earthworm, Lumbricus terrestris L. Z. Zellforsch. 54, 530–540 (1961).

    Google Scholar 

  • —, S. L. Palay and R. G. Nilges: The Nissl substance in secreting nerve cells. Anat. Rec. 92, 23–31 (1945).

    Google Scholar 

  • Schultz, R. L., E. A. Maynard and D. C. Pease: Electron microscopy of neurons and neuroglia of cerebral cortex and corpus callosum. Amer. J. Anat. 100, 369–408 (1957).

    Google Scholar 

  • Speidel, C. C.: Gland cells of internal secretion in the spinal cord of the skates. Pap. Dept. Mar. Biol. Carnegie Inst. Wash. 13, 1–31 (1919).

    Google Scholar 

  • —: Further comparative studies in other fishes of cells that are homologous to the large irregular glandular cells in the spinal cord of the skates. J. comp. Neurol. 34, 303–317 (1922).

    Google Scholar 

  • Welsh, J. H.: Neuroendocrine substances. In: Symposium on comparative Endocrinology held at Cold Spring Harbor, 1958 (Ed. A. Gorbman), pp. 121–133. New York: J. Wiley and Sons Inc. 1959.

    Google Scholar 

  • Wetzstein, R., W. Doerfler und A. Schwink: Die Feinstruktur der enterochromaffinen Zellen und ihrer spezifischen Granula. Protoplasma 55, 303–312 (1962).

    Google Scholar 

  • Yamada, E.: The fine structure of the renal glomerulus of the mouse. J. biophys. biochem. Cytol. 1, 551–566 (1955).

    Google Scholar 

  • Zetterquist, H.: The ultrastructural organization of the columnar absorbing cells of the mouse jejunum. Thesis, Karol. Inst., Stockholm 1956, pp. 1–82.

    Google Scholar 

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  1. Wenner-Gren Institute and the Zoological Institute, University of Stockholm, Sweden

    Björn A. Afzelius & Gunnar Fridberg

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  1. Björn A. Afzelius
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  2. Gunnar Fridberg
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Aided by grants from the Swedish Natural Science Research Council.

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Afzelius, B.A., Fridberg, G. The fine structure of the caudal neurosecretory system in Raia batis . Z. Zellforsch. 59, 289–308 (1963). https://doi.org/10.1007/BF00320449

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