Summary
The CML patients with so called masked Ph1-chromosome have been reviewed. Although the importance of c-sis and c-abl oncogenes is gaining popularity yet their role in the genesis of CML remain obscure. Patients with masked Ph1-chromosomes where chromosome 9 is not involved in the translocation(s) will provide a clue to the role of c-abl and/or c-sis in oncogenesis.
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Verma, R.S., Dosik, H. “Masked” Ph1-chromosome in chronic myelogenous leukaemia (CML). Blut 50, 129–133 (1985). https://doi.org/10.1007/BF00320068
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DOI: https://doi.org/10.1007/BF00320068