Summary
We present a report of the use of IgG i.v. to treat clinically manifest neonatal immune thrombocytopenia. The IgG i.v. was administered at a daily dosage of 0.4 g/kg body weight for 5 days. Treatment was started when the child was 3 days old and had a platelet count of 2×109/l. Four days later the platelet count had risen to 200×109/l. The diagnosis of immune thrombocytopenia was confirmed by platelet typing of the mother's and child's platelets and identification of anti-platelet antibodies in maternal serum.
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Sidiropoulos, D., Straume, B. The treatment of neonatal isoimmune thrombocytopenia with intravenous immunoglobin (IgG i.v.). Blut 48, 383–386 (1984). https://doi.org/10.1007/BF00319967
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DOI: https://doi.org/10.1007/BF00319967