Skip to main content
SpringerLink
Log in

Influence of chronic arsenic poisoning on bone marrow morphology

A case report

  • Short Communication
  • Published:
Blut Aims and scope Submit manuscript

Summary

Arsenic is widely used for the production of insecticides, paints, ceramics and for the preparation of textiles, leather and furs. Nevertheless hematologists are almost unaware of the influence of arsenic on bone marrow morphology. In the case described here we have found slight megaloblastic hemopoiesis, typical karyorrhexis in erythropoietic accompanied by basophilic stippling and impairment of mitoses in megakaryocytes and granulopoietic cells.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Dudley SF (1919) Toxemic anemia from arseniuretted hydrogen gas in submarines. D Industr Hgg 1: 215

    Google Scholar 

  2. Dustin AP (1927) Étude comparative entre l'action des radiations et l'action des poisons çaryoclastiques. Strasbourg Med 85: 12

    Google Scholar 

  3. Limarzi LR (1943) The effect of arsenic (Fowler's solution) on erythropoiesis, Am J med Sci 206: 339

    Google Scholar 

  4. Müller AH (1939) Die moderne Anämiebehandlung. In: K Beckmann (ed) Vorträge aus der praktischen Medizin. Ferdinand Enke Verlag, Stuttgart, p 22

    Google Scholar 

  5. Rohr K (1960) Pathophysiologie der Erythropoese. In: Das menschliche Knochenmark, 3, Aufl. Thieme Verlag, Stuttgart, p 237

    Google Scholar 

  6. Sack G (1941) Sternalmarkbefunde bei chronischer Arsenvergiftung der Winzer. Folia Haematol Leipz 64: 129

    Google Scholar 

  7. Storti E, Mauri C (1963) Chronisch myeloische Leukose von vorwiegend neutrophilem Typ. In: L Heilmeyer, A Hittmair (eds) Handbuch der gesamten Hämatologie, Bd IV, 2. Urban und Schwarzenberg, München Berlin p 165

    Google Scholar 

  8. Tempka T, Braun B (1932) Das morphologische Verhalten des Sternumpunktates in verschiedenen Stadien der perniziösen Anämie und seine Wandlung unter dem Einfluß der Therapie. Folia Haematol Leipz 48: 355

    Google Scholar 

  9. Wätjen J (1925) Über experimentelle toxische Schädigungen des lymphatischen Systems durch Arsen. Virchows Arch [Pathol Anat] 86: 256

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Zentrum für Innere Medizin der Justus-Liebig-Universität, Klinikstrasse 36, D-6300, Giessen, Federal Republic of Germany

    H. Pralle

  2. Neurologische Abteilung, Kreiskrankenhaus, Rintelner Strasse 85, D-4920, Lemgo, Federal Republic of Germany

    F. Manz

Authors
  1. H. Pralle
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F. Manz
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pralle, H., Manz, F. Influence of chronic arsenic poisoning on bone marrow morphology. Blut 50, 51–54 (1985). https://doi.org/10.1007/BF00319771

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00319771

Key words

Search

Navigation