Clinical and experimental investigations have shown that magnesium depletion causes a marked irritability of the nervous system, eventually resulting in epileptic seizures. Although magnesium deficiency as a cause of epilepsy is uncommon, its recognition and correction may prove life-saving. Two case reports are presented which emphasize the importance of recognizing hypomagnesaemia in patients with acute intractable seizures.
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Nuytten, D., Van Hees, J., Meulemans, A. et al. Magnesium deficiency as a cause of acute intractable seizures. J Neurol 238, 262–264 (1991). https://doi.org/10.1007/BF00319737