Summary
The occurrence of diazepam-binding inhibitor (DBI), isolated and characterized from porcine upper intestine, was examined in the pancreas of Sprague-Dawley albino rats using indirect immunofluorescence. The polypeptide was found in the endocrine Langerhans islets and, utilizing double-labelling controls, it was shown to be present within the peripherally located glucagon-containing cells. Regulation of islet hormone production may therefore be under DBI control.
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References
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Johansson, O., Hilliges, M., Östenson, CG. et al. Immunohistochemical localization of porcine diazepam-binding inhibitor (DBI) to rat endocrine pancreas. Cell Tissue Res 263, 395–398 (1991). https://doi.org/10.1007/BF00318781
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DOI: https://doi.org/10.1007/BF00318781