Summary
Forearm bone mineral density (BMD) was measured at proximal and distal sites by 125I single photon absorptiometry (SPA) and by dual energy X-ray absorptiometry (DXA) in 67 consecutive subjects, aged 18–75 years. Correlations and regression equations between these two techniques were determined. All forearm measurements were significantly correlated with each other (r=0.599–0.926; P≤0.0001). Although SPA and DXA correct for fat in different ways, we found similar correlation and regression equations in women with body mass index measurements above and below the mean. In addition, forearm measurements by both techniques were moderately correlated with vertebral spine and hip BMD. We conclude that overall, SPA forearm measurements in a population can be calibrated to DXA measurements if necessary, and that DXA forearm measurements are as predictive of the remainder of the skeleton as SPA measurements.
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References
Weinstein RS, New KD, Sappington LJ (1991). Dual-energy x-ray absorptiometry versus single photon absorptiometry of the radius. Calcif Tissue Int 49:313–316
Mazess RB, Barden HS (1988) Measurement of bone by dual-photon absorptiometry (DPA) and dual-energy x-ray absorptiometry (DEXA). Ann Chir Gynaecol 77:197–203
Cullum ID, Ell PJ, Ryder JP (1989) X-ray dual photon absorptiometry: a new method for the measurement of bone density. Br J Radiol 62:587–592
Johnson J, Dawson-Hughes B (1991) Precision and stability of dual-energy x-ray absorptiometry measurements. Calcif Tissue Int 49:174–178
Gluer CC, Steiger P, Selvidge R, Elliesen-Kliefoth K, Hayashi C, Genant HK (1990) Comparative assessment of dual-photon absorptiometry and dual-energy radiography. Radiology 174:223–228
Schlenker RA, VonSeggen WW (1976) The distribution of cortical and trabecular bone mass along the lengths of the radius and ulna and the implications for in vivo bone mass measurements. Calcif Tissue Res 20:41
Riggs BL, Melton LJ (1986) Involutional osteoporosis. N Engl J Med 314:1676–1686
Hui SL, Slemenda CW, Johnston CC Jr (1989) Baseline measurement of bone mass predicts fracture in white women. Ann Intern Med 111:355–361
Wasnich RD, Ross PD, Heilbrun LK, Vogel JM (1985) Prediction of postmenopausal fracture risk with the use of bone mineral measurements. J Obstet Gynecol 153:745–751
Johnston CC, Melton LJ, Lindsay R, Eddy DM (1989) Clinical indications for bone mass measurements. J Bone Miner Res 4 (suppl 2)
Cummings SR, Black DM, Nevitt MC, Browner WS, Cauley JA, Genant HK, Mascioli SR, Scott JC, Seeley DG, Steiger P, Vogt TM, Study of Osteoporotic Fractures Research Group (1990) Appendicular bone density and age predict hip fracture in women. The study of the Osteoporosis Fractures Research Group. JAMA 263:665–668
Christiansen C, Rodbro P, Jensen H (1975) Bone mineral content in the forearm measured by photon absorptiometry. Scand J Clin Lab Invest 35:323–330
Angell JE, Chung S, Curtis K, LeBoff MS (1991) Bone mineral density of the 1/3rd and ultradistal radius using dual x-ray absorptiometry. J Bone Miner Res 6 (suppl 1) S242
Cosman F, Schnitzer MB, McCann PD, Parisien MV, Dempster DW, Lindsay R (1992) Relationships between quantitative histological measurements and non-invasive assessments of bone mass. Bone 13:237–242
Christiansen C, Christiansen MS, McNair P, Hagen C, Stocklund KE, Transbol I (1980) Prevention of early postmenopausal bone loss. Eur J Clin Invest 2:273
Johnston CC Jr, Norton JA, Khairi RA, Longcope C (1979) Age-related bone loss. In: Barzel U (ed) Osteoporosis II. New York, Grune and Stratton
Melton LJ, Eddy DM, Johnston CC (1990) Screening for osteoporosis. Ann Intern Med 112:516–528
Lindsay R, Cosman F, Herrington BS, Himmelstein S (1992) Bone mass and body composition in normal women. J Bone Miner Res 7:55–63
Ross PD, Wasnich RD, Vogel JM (1988) Detection of prefracture spinal osteoporosis using bone mineral absorptiometry. J Bone Miner Res 3:1–11
Price RI, Barnes MP, Gutteridge DH, Baron-Hay M, Prince RL, Retallack RW, Hickling C (1989) Ultradistal and cortical forearm bone density in the assessment of postmenopausal bone loss and nonaxial fracture risk. J Bone Miner Res 4:149–155
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Nieves, J.W., Cosman, F., Mars, C. et al. Comparative assessment of bone mineral density of the forearm using single photon and dual X-ray absorptiometry. Calcif Tissue Int 51, 352–355 (1992). https://doi.org/10.1007/BF00316879
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DOI: https://doi.org/10.1007/BF00316879