Summary
Diclofenac sodium 0.5 mg/kg i. v. was given preoperatively to small children (age 4–6 y). Vt and total plasma clearance were higher than in adults but the elimination half-life was similar.
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Korpela, R., Olkkola, K.T. Pharmacokinetics of intravenous diclofenac sodium in children. Eur J Clin Pharmacol 38, 293–295 (1990). https://doi.org/10.1007/BF00315034
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DOI: https://doi.org/10.1007/BF00315034