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Positron emission tomography studies of neurotransmitter systems

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Summary

This article focuses on the use of positron emission tomography (PET) with radiolabelled pharmaceuticals as a quantitative tool for the measurement of neurotransmitter systems. We describe the methods of image acquisition and data analysis used to study the dopaminergic system and review the contribution of such studies to our understanding of movement disorders. PET studies of the opiate system are briefly reviewed and ongoing studies of benzodiazepine receptors, monoamine oxidase inhibitors and the serotoninergic system are described.

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Authors and Affiliations

  1. MRC Cyclotron Unit, Clinical Sciences Section, Hammersmith Hospital, 150 DuCane Road, W12 OHS, London, UK

    G. V. Sawle & D. J. Brooks

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  1. G. V. Sawle
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  2. D. J. Brooks
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Sawle, G.V., Brooks, D.J. Positron emission tomography studies of neurotransmitter systems. J Neurol 237, 451–456 (1990). https://doi.org/10.1007/BF00314760

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