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Lymphocyte concanavalin A capping in hereditary cerebral haemorrhage with amyloidosis — Dutch type

Journal of Neurology volume 237, pages 117–119 (1990)Cite this article

Summary

Lymphocyte capping with concanavalin A was studied in 11 patients with hereditary cerebral haemorrhage with amyloidosis (Dutch type) and 10 controls. No difference in capping was found between patients and controls. Abnormal lymphocyte concanavalin A capping has been reported in patients with the Icelandic type of cerebral amyloidosis and in patients with Alzheimer's disease, a disease in which cerebral amyloid angiopathy can also be found. The results suggest a difference in pathogenesis between the Dutch type of cerebral amyloidosis and the other amyloid diseases.

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Affiliations

  1. Department of Neurology, University Hospital, PO Box 9600, 2300 RC, Leiden, The Netherlands

    J. Haan, R. T. Demmers, O. J. S. Buruma & R. A. C. Roos

Authors
  1. J. Haan
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  2. R. T. Demmers
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  3. O. J. S. Buruma
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  4. R. A. C. Roos
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Members of the Amyloid Research Group, Leiden

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Haan, J., Demmers, R.T., Buruma, O.J.S. et al. Lymphocyte concanavalin A capping in hereditary cerebral haemorrhage with amyloidosis — Dutch type. J Neurol 237, 117–119 (1990). https://doi.org/10.1007/BF00314675

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  • DOI: https://doi.org/10.1007/BF00314675

Key words

  • Cerebral amyloid angiopathy
  • β-Protein
  • Peripheral blood lymphocytes