Skip to main content
SpringerLink
Log in

Multiple sclerosis associated with defective neuromuscular transmission

  • Short Communications
  • Published:
Journal of Neurology Aims and scope Submit manuscript

Zusammenfassung

Die klinische und elektromyographische Untersuchung einer 38jährigen Frau mit multipler Sklerose ergab Zeichen eines myasthenischen Syndromes. Bei der repetitiven Reizung des rechten Ulnarnerves mit hoher Frequenz und Ableitung von M. interosseus dorsalis I ergab sich eine Abnahme der Potentialgröße, jedoch keine Potenzierung. Nach der Reizung zeigte sich eine posttetanische Ermüdung. Nach Prostigmin war eine offensichtliche Verbesserung der neuromuskulären Reizübertragung sichtbar. Mögliche Mechanismen, welche eine Beziehung von multipler Sklerose und myasthenischem Syndrom erklären könnten, werden kurz diskutiert.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Bornstein, M.: Tissue culture studies of structural and functional alterations of the nervous system related to the demyelinative disorders. The Central Nerv. Syst. Int. Acad. Pathol. Monograph No. 9. Baltimore: Williams and Wilkins 1968

    Google Scholar 

  • Cendrowski, W.: Napadowa niezbornośé, napady skurczów tonicznych i napady poraźne w stwardnieniu rozsianym. Neurol. Neurochir. pol. 5, 109–114 (1971)

    Google Scholar 

  • Cendrowski, W.: Analiza historii chorób pod katem wystepowania krótkotrwalych pogorszeń i dobowej zmienności objawów u chorych ze stwardnieniem rozsianym. Neurol. Neurochir. pol. 7, 553–558 (1973)

    Google Scholar 

  • Field, E., Caspary, E.: Lymphocyte sensitization to thymus and lymph node antigen in multiple sclerosis and other neurological diseases. J. Neurol. Neurosurg. Psychiat. 36, 604–606 (1973)

    Google Scholar 

  • Goldstein, G., Hoffmann, W.: Experimental myasthenia gravis. Immunological disorders of the nervous system (ed. L. Rowland). Baltimore: Williams and Wilkins 1971

    Google Scholar 

  • Hokkanen, E., Pirskanen, R., Bergström, L.: Simultaneous occurrence of demyelinating disease and the myasthenic syndrome. A report of three cases. Xth Cong. of Neurology. Excerpta Med. Found., Amsterdam, 1973

  • Keane, J., Hoyt, W.: Myasthenic (vertical) nystagmus. Verification by edrophonium tonography. J. Amer. med. Ass. 212, 1209–1211 (1970)

    Google Scholar 

  • Kott, E., Rule, A.: Myasthenia gravis. Neurology 23, 745–748 (1973)

    Google Scholar 

  • Kuligowski, Z.: Sclerose en plaques avec signes pseudomyastheniques. Rev. Neurol. 70, 347–348 (1938)

    Google Scholar 

  • Margolis, L., Graves, R.: Occurrence of myasthenia gravis in a patient with multiple sclerosis. N. Carol. Med. J. 6, 243–246 (1945)

    Google Scholar 

  • Patten, B., Hart, A., Lovelace, R.: Multiple sclerosis associated with defects in neuromuscular transmission. J. Neurol. Neurosurg. Psychiat. 35, 385–392 (1972)

    Google Scholar 

  • Riekkinen, P., Rinne, U.: In press

  • Voiculescu, U., Pruskauer-Apostol, B., Alecu, C.: Treatment of brain stem and spinal paroxysmal disorders in multiple sclerosis with acetazolamide. Xth Cong. of Neurology. Excerpta Med. Found., Amsterdam, 1973

Download references

Author information

Authors and Affiliations

  1. The Institute of Psychiatry and Neurology, Warsaw, Poland

    Wojciech Cendrowski

Authors
  1. Wojciech Cendrowski
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cendrowski, W. Multiple sclerosis associated with defective neuromuscular transmission. J. Neurol. 209, 297–299 (1975). https://doi.org/10.1007/BF00314369

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00314369

Key words

Search

Navigation