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Familial adrenoleukodystrophy: long chain fatty acid levels and analysis with a factor VIII DNA probe

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Summary

Segregation studies of X-linked adrenoleukodystrophy (ALD) and a cloned desoxyribonucleic fragment (factor VIII gene), which detects polymorphism in the distal end of the long arm of the X chromosome (Xq28), are reported in a large sibship ALD family. The findings should permit better identification of carriers and add a new marker for identifying the ALD gene itself.

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Authors and Affiliations

  1. Laboratory of Molecular Genetics, INTS, 6 rue Alexandre Cabanel, Paris, France

    S. Berriche & G. Lucotte

  2. Service of Neurology, Robert Debré Hospital, rue Alexis Carel, Reims, France

    J. C. Turpin

Authors
  1. S. Berriche
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  2. J. C. Turpin
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  3. G. Lucotte
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Berriche, S., Turpin, J.C. & Lucotte, G. Familial adrenoleukodystrophy: long chain fatty acid levels and analysis with a factor VIII DNA probe. J Neurol 235, 234–235 (1988). https://doi.org/10.1007/BF00314353

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  • DOI: https://doi.org/10.1007/BF00314353

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