Summary
After 1 year of exposure to trichloroethylene, reversible neuropsychological impairment and persistent EEG paroxysms were observed in one patient. The improvement of neuropsychological performances and the persistence of severe EEG abnormalities after withdrawal of the toxin suggest “functional” cerebral damage after prolonged exposure to trichloroethylene.
References
Brickenkamp R (1962) Test d2 Aufmerksamkeits-Belastungstest. Verlag für Psychologie CJ Hogrefe, Göttingen
Caltagirone C, Gainotti G, Masullo C, Miceli G (1979) Validity of some neuropsychological tests in the assessment of the mental deterioration. Acta Psychiatr Scand 60:50–56
Feldman RG (1979) Trichloroethylene. In: Vinken PJ, Bruyn GW (eds) Handbook of clinical neurology, vol 36. North-Holland Publishing Company, Amsterdam, pp 457–464
Gainotti G, Caltagirone C, Diodato S, Grappone A (1983) Neuropsychological assessment in aging brain: the distinction between dementia and progressive pseudo-dementia. In: Cecchini A, Nappi G, Arrigo A (eds) Cerebral pathology in old age. Emiras, Pavia, pp 7–16
Giuliano G, Iannaccone A, Zappoli R (1974) Ricerche elettroencefalografiche in operai di calzaturifici esposti al rischio di intossicazione da solventi. Lav Um 26:3–42
Grandjean E, Münchingen F, Turrien V, Haas PA, Knoepfel HK, Rosenmund H (1955) Investigations into the effect of exposure to trichloroethylene in mechanical engineering. Br J Ind Med 12:131–142
Juntunen J, Antti-Poika M, Tola S, Partanen T (1982) Clinical prognosis of patients with diagnosed chronic solvent intoxication. Acta Neurol Scand 65:488–503
Konietzko H, Elster I, Sayer H, Weichardt H (1975) Zentralnervöse Schäden durch Trichloräthylen. Staub-Reinhalt 35:240–241
Lindström K (1980) Changes in psychological performances of solvent-poisoned and solvent-exposed workers. Am J Ind Med 1:69–84
Lindström K (1982) Behavioural effects of long-term exposure to organic solvents. Acta Neurol Scand 66 [Suppl 92]:131–141
Seppäläinen AM, Lindström K, Martelin T (1980) Neurophysiological and psychological picture of solvent poisoning. Am J Ind Med 1:31–42
Triebig G, Schaller KH, Erzigkeit H, Valentin H (1977) Biochemische Untersuchungen und psychologische Studien an chronisch Trichloräthylenbelasteten Personen unter Berücksichtigung expositionsfreier Intervalle. Int Arch Occup Environ Health 38:149–162
Woodworth RS, Schlosberg H (1958) Experimental psychology. Methuen, London
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Stracciari, A., Gallassi, R., Ciardulli, C. et al. Neuropsychological and EEG evaluation in exposure to trichloroethylene. J Neurol 232, 120–122 (1985). https://doi.org/10.1007/BF00313914
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00313914