Skip to main content
SpringerLink
Log in

Becker muscular dystrophy: carrier detection by real-time ultrasound

  • Original Investigations
  • Published:
Journal of Neurology Aims and scope Submit manuscript

Summary

The applicability was tested of real-time ultrasound imaging to the thigh musculature for the carrier detection of Becker muscular dystrophy (BMD). A total of 17 obligate carriers were examined. Ultrasound images in 3 patients, aged between 46 and 59 years, showed moderate differences compared with the controls. In 3 other obligate carriers, aged between 46 and 71 years, only doubtfully abnormal findings could be made; ultrasound images showed no differences in 11 BMD carriers aged between 10 and 47 years. In women aged over 40 years, compared with adequate controls of the same body type, real-time ultrasound imaging may provide additional evidence and thus help in the detection of BMD carriers.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Becker PE, Kiener F (1955) Eine neue X-chromosomale Muskeldystrophie. Arch Psychiatr Nervenkr 193:427–448

    Google Scholar 

  2. Heckmatt JZ, Dubowitz V (1983) Detecting the Duchenne carrier by ultrasound and computerised tomography. Lancet ii:1364

    Google Scholar 

  3. Heckmatt JZ, Dubowitz V, Leeman S (1980) Detection of pathological change in dystrophic muscle with B-scan ultrasound imaging. Lancet i:1389–1390

    Google Scholar 

  4. Heckmatt JZ, Leeman S, Dubowitz V (1982) Ultrasound imaging in the diagnosis of muscle disease. J Pediatr 101:656–660

    Google Scholar 

  5. Herrmann FH, Spiegler AWJ (1983) Carrier detection in X-linked Becker muscular dystrophy by muscle provocation test (MPT). J Neurol Sci 62:141–146

    Google Scholar 

  6. Rott HD, Mulz D (1982) Muskeldystrophie Duchenne: Konduktorinnenerfassung mit Ultraschall. Dtsch Med Wochenschr 107:1678–1681

    Google Scholar 

  7. Spiegler AWJ, Herrmann FH (1983) Ascertainment and genetic counseling of risk families with Duchenne muscular dystrophy (DMD) or Becker muscular dystrophy (BMD) in the district Erfurt. Dtsch Gesundheitswes 38:995–1000

    Google Scholar 

  8. Spiegler AWJ, Wiedemann G, Herrmann FH, Menzel K, Hoffmann W, Thomas A, Strobel U (1982) Altersabhängigkeit der Creatinkinase-(CK) Aktivität bei Duchenne Muskeldystrophie (DMD). Dtsch Gesundheitswes 37:2009–2013

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Medizinische Akademie Erfurt, Abteilung Medizinische Genetik, Klement-Gottwald-Str. 34, DDR-5082, Erfurt, German Democratic Republic

    Aribert W. J. Spiegler

  2. Katholisches Krankenhaus „St. Nepomuk“, Kartäuserstr. 64, DDR-5020, Erfurt, German Democratic Republic

    Siegfried Schindler

  3. Ernst-Moritz-Arndt-Universität, Institut für Medizinische Genetik, Fleischmannstr. 42/44, DDR-2200, Greifswald, German Democratic Republic

    Falko H. Herrmann

Authors
  1. Aribert W. J. Spiegler
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Siegfried Schindler
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Falko H. Herrmann
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Spiegler, A.W.J., Schindler, S. & Herrmann, F.H. Becker muscular dystrophy: carrier detection by real-time ultrasound. J Neurol 232, 307–309 (1985). https://doi.org/10.1007/BF00313871

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00313871

Key words

Search

Navigation