Skip to main content

Samuel Auguste Tissot (1728–1797) His research on migraine


The famous Swiss physician of the eighteenth century, Samuel Auguste André David Tissot, devoted an 83-page chapter to migraine in his Traité des nerfs et de leurs maladies (Treatise on the nerves and nervous disorders). From his own personal observations and an exhaustive critical review of the medical literature, he described in clear terms the signs and symptoms and the clinical course of the disease, made known his findings to contemporary physicians and created a basis for research for future generations of doctors. In so doing, he fully deserves his high reputation as the classical authority on migraine.

This is a preview of subscription content, access via your institution.


  1. Bucher HW (1958) Tissot und sein Traité des nerfs. M.D. Thesis, Zürich

  2. Isler H (1970) Aus der Geschichte der Migräne, vol I. Bücherreihe Hommel, Adliswil Zürich, pp 9–23

  3. Kehr K (1905) Zur historischen Entwicklung der Lehre vom Kopfschmerz. M.D. Thesis, Freiburg im Breisgau

  4. Möbius PJ (1894) Die Migräne. Hölder, Vienna

    Google Scholar 

  5. Sacks O (1973) Migraine. The evolution of a common disorder. Faber and Faber, London

    Google Scholar 

  6. Thomas L (1887) La migraine. Delahaye et Lecrosnier, Paris

    Google Scholar 

  7. Tissot SA (1770) Traité de l'épilepsie, Faisant le Tome troisieme du Traité des nerfs et de leurs maladies. Chapuis, Lausanne et Didot, le jeune, Paris. Facsimile-Edition in: Karbowski K (1984) Samuel Auguste Tissot et son “Traité de l'épilepsie” de 1770. Fondation Eben-Hezer, Lausanne

    Google Scholar 

  8. Tissot SA (1780) Traité des nerfs et de leurs maladies, vol III, pt II. Didot, le jeune, Paris-Lausanne

    Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Cite this article

Karbowski, K. Samuel Auguste Tissot (1728–1797) His research on migraine. J Neurol 233, 123–125 (1986).

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI:

Key words

  • Migraine
  • Tissot
  • History of medicine