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Autonomic dysfunction in polyneuropathies: a report on 106 cases

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Summary

Autonomic dysfunction is a common feature in various forms of polyradiculoneuropathy. This study investigated the kinds and frequency of autonomic dysfunction in 106 cases. Denervation insufficiency of organs associated with supersensitivity of reflex mechanisms was found to be the best explanation of the pathophysiology. Early insertion of a transient cardiac pacemaker is recommended to counteract life-threatening cardiac failure.

Zusammenfassung

Autonome Funktionsstörungen sind eine häufige Begleiterscheinung im Rahmen von Polyradiculoneuropathien. Die vorliegende Studie untersucht anhand von 106 Fällen die Art und Häufigkeit derartiger Störungen. Die pathophysiologischen Mechanismen werden diskutiert, wobei sich ein denervationsbedingter Funktionsausfall betroffener Organe in Verbindung mit einer Denervierungsüberempfindlichkeit der Reflexmechanismen als beste Erklärung anbietet. Als therapeutische Konsequenz wird der frühzeitige Einsatz eines temporären Herzschrittmachers empfohlen, um lebensbedrohlichen kardialen Komplikationen begegnen zu können.

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Authors and Affiliations

  1. Neurologische Universitätsklinik, Josef-Schneider-Str. 11, D-8700, Würzburg, Federal Republic of Germany

    A. Krone, P. Reuther & U. Fuhrmeister

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  1. A. Krone
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  2. P. Reuther
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  3. U. Fuhrmeister
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Krone, A., Reuther, P. & Fuhrmeister, U. Autonomic dysfunction in polyneuropathies: a report on 106 cases. J Neurol 230, 111–121 (1983). https://doi.org/10.1007/BF00313638

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