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Ophthalmic herpes zoster with contralateral hemiparesis: a case report

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Summary

Herpes zoster of the ophthalmic division of the left fifth cranial nerve with contralateral hemiparesis was observed in a 30-year-old man. Left carotid angiography showed segmental constrictions consistent with cerebral arteritis, possibly provoked by direct viral infection along the intracranial part of the ophthalmic nerve. An ischaemic lesion revealed by computed tomographic scan was considered secondary to arteritis and responsible for the hemiparesis. The presence of an immune response within the blood-CSF barrier was suggested by an increase of oligoclonal CSF IgG and IgA.

Zusammenfassung

Bei einem 30jährigen Manne trat ein linksseitiger Herpes zoster ophthalmicus mit einer Hemiparese auf der rechten Körperseite auf. Eine linksseitige Carotisangiographie zeigte eine segmentale Einengung, die vereinbar war mit einer Arteriitis. Man erwog eine direkte Einwirkung des Virus, ausgehend vom intracraniellen Anteil des N. ophthalmicus. Im Computertomogramm des Schädels war eine ischämische Zone nachweisbar, die als sekundäre Auswirkung der Arteriitis angesehen wurde und das zentralnervöse Substrat der Hemiparese darstellte. Die Zunahme eines oligoklonalen IgGs und IgA im Liquor wies auf eine Immunantwort innerhalb der Blut-Liquor-Schranke hin.

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Federico, F., Pedone, D., Lamberti, P. et al. Ophthalmic herpes zoster with contralateral hemiparesis: a case report. J Neurol 228, 283–287 (1982). https://doi.org/10.1007/BF00313419

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  • DOI: https://doi.org/10.1007/BF00313419

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