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Intraventricular administration of rifampin for tuberculous meningitis

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Summary

A case of tuberculous meningitis associated with cerebral tuberculomas, and resistant to antituberculous therapy is reported. Repeated injections of rifampin, administered through an intraventricular Ommaya drain, provided an effective control of the meningeal infection.

Zusammenfassung

Es wird ein Fall von tuberkulöser Hirnhautentzündung bei zerebralen Tuberkulomen geschildert, die auf die übliche tuberkulostatische Behandlung nicht reagierte. Es gelang hingegen, die Entzündung erfolgreich durch die wiederholte Zufuhr von Rifampin durch einen intraventrikulären Ommaya-Katheter zu beheben.

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Reference

  1. Lee EL, Robinson MJ, Thong ML, Puthucheary SD, Ong TH, Ny KK (1977) Intraventricular chemotherapy in neonatal meningitis. J Pediatr 91:991–995

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Authors and Affiliations

  1. Brugmann Hospital, Free University of Brussels, Brussels, Belgium

    P. Dajez, W. Vincken, D. Lambelin, J. Noterman, E. Yourassowski & N. Telerman-Toppet

  2. Service of Neurosurgery, Belgium

    J. Noterman

Authors
  1. P. Dajez
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  2. W. Vincken
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  3. D. Lambelin
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  4. J. Noterman
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  5. E. Yourassowski
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  6. N. Telerman-Toppet
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Dajez, P., Vincken, W., Lambelin, D. et al. Intraventricular administration of rifampin for tuberculous meningitis. J Neurol 225, 153–156 (1981). https://doi.org/10.1007/BF00313328

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  • DOI: https://doi.org/10.1007/BF00313328

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