Summary
Serum myoglobin was measured by a sensitive radioimmunoassay in healthy controls and patients with primary and secondary skeletal muscle disorders. The results indicate that serum myoglobin is a useful parameter in the assessment of muscle damage.
Zusammenfassung
Die Serum-Myoglobinkonzentration wurde mit einem empfindlichen Radioimmunoassay bei gesunden Kontrollpersonen und Patienten mit primären und sekundären Skelettmuskelerkrankungen gemessen. Die Ergebnisse lassen erkennen, daß die Myoglobinkonzentration im Serum einen nützlichen Parameter bei der Beurteilung von Muskelzellschäden darstellt.
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References
Adams EC, Layman KM, Jaunakais I (1978) Radioimmunoassay for serum myoglobin. Ann clin Lab Sci 8:330–341
Hische EAH, van der Helm HJ (1979) The significance of serum myoglobin in neuromuscular diseases. J Neurol Sci 43:243–251
Kagen L, Scheidt S, Roberts L (1975) Myoglobinemia following acute myocardial infarction. Am J Med 58:177–182
Kagen L, Scheidt S, Butt A (1977) Serum myoglobin in myocardial infarction: the staccato phenomenon. Am J Med 62:86–92
Kasai K (1979) Serum myoglobin level in altered thyroid states. J Clin Endocrinol Metab 48:1–4
Levine RS, Allerman M, Gubner RS, Adams EC (1971) Myoglobinuria in myocardial infarction. Am J Med Sci 262:179–183
Miyoshi K, Saito S, Kawai H, Kondo A, Iwas M, Hayashi T, Yagita M (1978) Radioimmunoassay for human myoglobin: method and results in patients with skeletal muscle and myocardial disorders. J Lab Clin Med 92:341–352
Rosano TG, Sanders LA, Johnson ES, Kenny MA, Clayson KJ, Strandjord PE (1977) Myoglobin concentrations and muscle enzyme activities in serum after myocardial infarction and cardiac arrhythmia. Clin Chem 23:868–870
Saranchak HJ, Bernstein SH (1974) A new diagnostic test for acute myocardial infarction. JAMA 228:1251–1255
Stone MJ, Willerson JT, Gomez-Sanchez CE, Waterman MR (1975) Radioimmunoassay of myoglobin in human serum. J Clin Invest 56:1334–1339
Stone MJ, Waterman MR, Harimoto D, Murray G, Willson N, Platt MR, Blomquist G, Willerson JT (1977) Serum myoglobin level as a diagnostic test in patients with acute myocardial infarction. Brit Heart J 39:375–380
Volk P, Fittschen U, Begemann M (1973) Myoglobin im Serum nach Herzinfarkt. Münch Med Wochenschr 115:2122–2128
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Supported by the German Society of Neurology, ALS-Fond
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Kiessling, W.R., Ricker, K., Pflughaupt, K.W. et al. Serum myoglobin in primary and secondary skeletal muscle disorders. J Neurol 224, 229–233 (1981). https://doi.org/10.1007/BF00313285
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DOI: https://doi.org/10.1007/BF00313285