Zusammenfassung
In normalem Gehirngewebe und in Gehirngewebe einer Niemann-Pickschen Erkrankung vom Typus A wurden Glykosphingolipide unter Verwendung der Dünnschichtchromatographie und der Flüssig-Gaschromatographie bestimmt. Bei der Niemann-Pickschen Erkrankung fand sich eine Zunahme der Ceramid-Trihexoside, die durch Digalactosylglucosylceramide bedingt war. Auch das Glucosylcerebrosid war vermehrt.
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Greenbaum, M., Hoffman, L.M. & Schneck, L. Ceramide hexosides in niemann-pick disease brain. J. Neurol. 213, 251–255 (1976). https://doi.org/10.1007/BF00312874
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DOI: https://doi.org/10.1007/BF00312874