The efficacy of a reinforced biosynthetic ovine collagen (RBOC) vascular prosthesis developed for small arterial reconstruction was assessed by examining 30 grafts in 29 patients with arteriosclerosis obliterans. The operative procedures performed were femorofemoral bypass in 2 patients, above-knee femoropopliteal bypass in 28 patients, and below-knee femoropopliteal bypass in 1 patient. Femoropopliteal bypass was simultaneously performed in two patients undergoing femorofemoral bypass using one or two grafts. The indications for surgery were intermittent claudication in 27 patients and to salvage the limb in 2 patients. The longest follow-up period was 49 months, and there were six graft failures, occurring 1, 1, 9, 17, 17, and 23 months after implantation, respectively; caused by compression of the graft from outside in two, infection in one, anastomotic intimal hyperplasia in one, and unknown factors in two. Thus, the primary cumulative patency rate for above-knee femoropopliteal bypass at 3 years was 83.7%, and the secondary patency rate was 91.2%. No aneurysmal change was observed. Moreover, the RBOC was able to be used without preclotting, and its handling and suturing characteristics were satisfactory. Our findings suggest that this vascular prosthesis may be an acceptable alternative for above-knee femoropopliteal bypass.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Yoshida H, Sasajima T, Inaba M, Morimoto N, Otani N, Kubo Y (1992) An experimental and clinical study of the reinforced biosynthetic ovine collagen vascular prosthesis (Omniflow) for small vessel reconstruction (in Japanese with English abstract). Jinko Zoki (Jpn J Artif Organs) 21:1231–1235
Ketharnathan V, Christie BA (1980) Glutaraldehyde-tanned ovine collagen conduits as vascular xenografts in dogs — a preliminary report. Arch Surg 115:967–969
Perloff LJ, Christie BA, Ketharanathan V, Field PL, Milne PY, MacLeish DG, Royal G (1981) A new replacement for small vessels. Surgery 89:31–41
Christie BA, Ketharanathan V, Perloff LJ (1982) Minute vascular replacements. Arch Surg 117:1290–1294
Yoshida H, Kubo Y, Sasajima T, Nishioka Y, Izumi Y, Naoe A, Morimoto N, Nakayama K, Sakai H, Samejima N (1987) An experimental study of the vascular bioprostheses for small vessel reconstruction (in Japanese with English abstract). Jinko Zoki (Jpn J Artif Organs) 16:1514–1517
Hallin RW, Sweetman WR (1976) The Sparks' mandril graft. A seven-year follow-up of mandril grafts placed by Charles H. Sparks and his associates. Am J Srug 132:221–223
Guidoin R, Noël HP, Marois M, Martin L, Laroche F, Béland L, Côté R, Gosselin C (1980) Another look at the Sparks-mandril arterial graft precursor for vascular repair — pathology by scanning electron microscopy. Biomat Med Dev Artif Organs 8:145–167
Sasajima T (1984) Preserved human umbilical cord vessel as a small-caliber vascular substitute: experimental and clinical study (in Japanese with English abstract). Nippon Geka Gakkai Zasshi (J Jpn Surg Soc) 85:65–76
Kokubo M (1988) Influence of flow disturbance on an anastomotic intimal hyperplasia: experimental and clinical study (in Japanese with English abstract). Nippon Geka Gakkai Zasshi (J Jpn Surg Soc) 89:1707–1715
About this article
Cite this article
Yoshida, H., Sasajima, T., Goh, K. et al. Early results of a reinforced biosynthetic ovine collagen vascular prosthesis for small arterial reconstruction. Surg Today 26, 262–266 (1996). https://doi.org/10.1007/BF00311585
- collagen vascular prosthesis
- vascular bioprosthesis
- ovine graft
- above-knee femoropopliteal bypass