Skip to main content
SpringerLink
Log in

On animal models for studying bone adaptation

  • Letters to the Editor
  • Published:
Calcified Tissue International Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Torrence AG, Mosley JR, Suswillo RFL, Lanyon LE (1994) Noninvasive loading of the rat ulna in vivo induces a strainrelated modeling response uncomplicated by trauma or periosteal pressure. Calcif Tissue Int 54:241–247

    Google Scholar 

  2. Jee WSS, Li XJ (1990) Adaptation of cancellous bone to overloading in the adult rat: a single photon absorptiometry and histomorphometry study. Anat Rec 227:418–426

    Google Scholar 

  3. Jee WSS, Li XJ, Schaffler MB (1991) Adaptation of diaphyseal structure with aging and increased mechanical usage in the adult rat: a histomorphometrical and biomechanical study. Anat Rec 230:332–338

    Google Scholar 

  4. Turner CH, Akhter MP, Raab DM, Kimmel DB, Recker RR (1991) A noninvasive, in vivo model for studying strain adaptive bone modeling. Bone 12:73–79

    Google Scholar 

  5. Turner CH, Woltman TA, Belongia DA (1992) Structural changes in rat bone subjected to long-term, in vivo mechanical loading. Bone 13:417–422

    Google Scholar 

  6. Turner CH, Forwood MR, Rho J-Y, Yoshikawa T (1994) Mechanical loading thresholds for lamellar and woven bone formation. J Bone Miner Res 9:87–97

    Google Scholar 

  7. Raab-Cullen DM, Akhter MP, Kimmel DB, Recker RR (1994) Bone response to alternate-day mechanical loading of the rat tibia. J Bone Miner Res 9:203–211

    Google Scholar 

  8. Forwood MR, Turner CH (1994) Mechanotransduction in the rat tibia is frequency dependent. Trans 40th Orthop Res Soc Meeting, p 277

  9. Raab-Cullen DM, Kimmel DB, Akhter MP, Recker RR (1994) Transient increase in bone formation after external mechanical loading. Trans 40th Orthop Res Soc Meeting, p 276

  10. Chambers TJ, Evans M, Gardner TN, Turner-Smith A, Chow JWM (1993) Induction of bone formation in rat tail vertebrae by mechanical loading. Bone Miner 20:167–178

    Google Scholar 

  11. Chow JWM, Jagger CJ, Chambers TJ (1993) Characterization of osteogenic response to mechanical stimulation in cancellous bone of rat caudal vertebrae. Am J Physiol 265:E340-E347

    Google Scholar 

  12. Akhter MP, Raab DM, Turner CH, Kimmel DB, Recker RR (1992) Characterization of in vivo in the rat tibia during external application of a four-point bending load. J Biomech 25:1241–1246

    Google Scholar 

References

  1. Torrance A, Mosley J, Suswillo R, Lanyon L (1994) Noninvasive loading of the rat ulna in vivo induces a strain-related modeling response uncomplicated by trauma or periosteal pressure. Calcif Tissue Int 54:241–247

    Google Scholar 

  2. Turner CH, Akhter MP, Raab DM, Kimmel DB, Recker RR (1991) A non-invasive, in vivo model for studying strain adaptive bone modeling. Bone 12:73–79

    Google Scholar 

  3. Turner CH, Woltman T, Belongia D (1992) Structural changes in rat bone subjected to long-term, in vivo mechanical loading. Bone 13:417–422

    Google Scholar 

  4. Turner CH, Forwood MR, Rho JY, Yoshikawa T (1994) Mechanical thresholds for lamellar and woven bone formation. J Bone Min Res 9:878–997

    Google Scholar 

  5. Akhter MP, Raab DM, Turner CH, Kimmel DB, Recker RR (1992) Characterization of in vivo strain in the rat tibia during external application of a four-point bending load. J Biomech 25:1241–1246

    Google Scholar 

  6. Hagino H, Raab D, Kimmel D, Akhter M, Recker R (1993) The effects of ovariectomy on bone response to in vivo external loading. J Bone Min Res 8:347–357

    Google Scholar 

  7. Raab-Cullen D, Akhter M, Kimmel D, Recker R (in press) Bone response to alternate day mechanical loading of the rat tibia. J Bone Min Res

  8. Raab-Cullen D, Akhter M, Kimmel D, Recker R (in press) Periosteal bone formation is stimulated by externally induced bending strains. J Bone Min Res

  9. Raab-Cullen D, Kimmel D, Akhter M, Recker R (1993) Transient increase in bone formation after external mechanical loading. Submitted to Orthop Res Soc for presentation (abstract)

  10. Mosley J, Lanyon L (1994) Adaptive modelling in response to controlled, non-invasive mechanical loading in the rat ulna in vivo. Transactions of the 40th Orthopedic Research Society Meeting 19:33

    Google Scholar 

  11. Lanyon LE, Goodship AE, Pye CJ, MacFie JH (1982) Mechanically adaptive bone remodelling. J Biomech 15:141–154

    Google Scholar 

  12. Rubin CT, Lanyon LE (1985) Regulation of bone mass by mechanical strain magnitude. Calcif Tissue Int 37:411–417

    Google Scholar 

  13. Burr DB, Schaffler M, Yang K, Wu D, Lukoschek M, Kandzari D, Sivaneri N, Blaha J, Radin E (1989) The effects of altered strain environment on bone tissue kinetics. Bone 10:215–221

    Google Scholar 

  14. Chambers T, Evans M, Gardner T, Turner-Smith A, Chow J (1993) Induction of bone formation in rat tail vertebrea by mechanical loading. Bone Miner 20:167–178

    Google Scholar 

References

  1. Torrance AG, Mosley JR, Suswillo RFL, Lanyon LE (1994) Noninvasive loading of the rat ulna in vivo induces a strainrelated modeling response uncomplicated by trauma or periosteal pressure. Calcif Tissue Int 54:241–247

    Google Scholar 

  2. Hert J, Liskova M, Landa J (1971) Reaction of bone to mechanical stimuli, Part 1: continuous and intermittent loading of tibia in rabbit. Folia Morphologica (Praha) 19:290–300

    Google Scholar 

  3. O'Connor JA, Lanyon LE, MacFie H (1982) The influence of strain rate on adaptive bone remodeling. J Biomechanics 15:767–781

    Google Scholar 

  4. Lanyon LE, Rubin CT (1984) Static versus dynamic loads as an influence on bone remodeling. J Biomechanics 17:897–905

    Google Scholar 

  5. Rubin CT, Lanyon LE (1984) Regulation of bone formation by applied dynamic loads. J Bone Joint Surg [Br] 66-A:397–402

    Google Scholar 

  6. Turner CH, Akhter MP, Raab DM, Kimmel DB, Recker RR (1991) A non-invasive, in vivo model for studying strain-adaptive bone modeling. Bone 12:73–79

    Google Scholar 

  7. Turner CH, Forwood MR, Rho JY, Yoshikawa T (1994) Mechanical thresholds for lamellar and woven bone formation. J Bone Miner Res 9:987–997

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Indiana University Medical Center, 46202, Indianapolis, Indiana, USA

    C. H. Turner & M. R. Forwood

  2. Indiana University Medical Center, 601 North 30th Street, Suite #5740, 68131, Omaha, Nebraska, USA

    D. M. Raab-Cullen, M. P. Akhter, D. B. Kimmel & R. R. Recker

  3. The Royal Veterinary College, London, UK

    A. G. Torrance & L. E. Lanyon

Authors
  1. C. H. Turner
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. R. Forwood
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D. M. Raab-Cullen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. P. Akhter
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. D. B. Kimmel
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. R. R. Recker
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. A. G. Torrance
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. L. E. Lanyon
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Turner, C.H., Forwood, M.R., Raab-Cullen, D.M. et al. On animal models for studying bone adaptation. Calcif Tissue Int 55, 316–318 (1994). https://doi.org/10.1007/BF00310412

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00310412

Keywords

Search

Navigation