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Effects of direct current on renal function

An experimental study in pigs

Summary

Electric current from an external source was introduced between electrodes operatively placed into the ureters and positioned in the renal pelves of 13 pigs. Urinary excretion via the cathodic kidney showed a marked increase. The renal plasma flow and glomerular filtration rate diminished with increasing voltage, but no significant difference was found between the cathodic and the anodic kidney. The fractional sodium excretion by the cathodic kidney was 80% higher, indicating that the electric current mainly affected tubular function. A possible clinical application for electric fields in the kidneys is discussed.

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Kinn, A.C., Nordenström, B.E.W., Elbarouni, J. et al. Effects of direct current on renal function. Urol. Res. 19, 397–400 (1991). https://doi.org/10.1007/BF00310159

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  • DOI: https://doi.org/10.1007/BF00310159

Key words

  • Application of electric fields in the kidneys
  • Renal function
  • Unilateral electrolyte excretion
  • Cathodic excretion of fluid