Abstract
Yeast rgs1 cells accumulate secretory vesicles in the cytoplasm and stop the secretion of proteins at the restrictive temperature. The ts mutation rgs1 may be suppressed by several different genes; the S. cerevisiae SEC4 gene, encoding the small G-protein involved in the late secretory stage, is one of them. Synthetic lethality of the double rgs1 sec4 mutant is demonstrated.
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Communicated by P. P. Slonimski
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Gerassimenko, O.G. Yeast ts secretory mutation rgs1 is suppressed by the SEC4 gene of Saccharomyces cerevisiae . Curr Genet 25, 178–179 (1994). https://doi.org/10.1007/BF00309545
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DOI: https://doi.org/10.1007/BF00309545