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Occurrence of intraperitoneal septic complications after hepatic resections between 1985 and 1990

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Abstract

In this study, the risk factors related to intraperitoneal septic complications occurring after hepatectomy (IPSCH) as well as the effect of various perioperative variables on the outcome of IPSCH between 1985 and 1990 were analyzed. Twenty-one of 211 patients (10.0%) developed IPSCH. The findings in the patients with IPSCH were compared with those in 190 patients without IPSCH. The significant variables associated with the development of IPSCH included a high incidence of accompanying chronic renal failure (14.3% vs 2.1%), a larger blood loss during surgery (2,130 vs 1,340 ml) as well as a greater amount of intraoperative blood replacement (1,130 vs 570 ml), and a greater weight of the resected liver (367 vs 233g). IPSCH occurred in 10 of 12 patients who had postoperative bile leakage. Eighteen patients (85.7%) with IPSCH were discharged from the hospital after non-operative management; however, the hospital death rate (14.3% vs 1.1%) was significantly higher in patients with IPSCH. This review suggests that the incidence of IPSCH has not decreased recently. Thus, to prevent IPSCH, at least following bile leakage, it is necessary to perform a careful division of the liver parenchyma followed by a bile leakage test, and when this complication occurs unexpectedly in patients who have a good functional reserve of the remnant liver, IPSCH can be effectively drained percutaneously under ultrasound guidance.

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References

  1. Matsumata T, Kanematsu T, Shirabe K, Sonoda T, Furuta T, Sugimachi K (1990) Decreased morbidity and mortality rates in surgical patients with hepatocellular carcinoma. Br J Surg 77:677–680

    Google Scholar 

  2. Franco D, Smadja C, Meakins JL, Wu A, Berthoux L, Grange D (1989) Improved early results of elective hepatic resection for liver tumors: one hundred consecutive hepatectomies in cirrhotic and noncirrhotic patients. Arch Surg 124:1033–1037

    Google Scholar 

  3. Chen MF, Hwang TL, Jeng LBB, Jan YY, Wang CS, Chou FF (1989) Hepatic resection in 120 patients with hepatocellular carcinoma. Arch Surg 124:1025–1028

    Google Scholar 

  4. Nagorney DM, van Heerden JA, Ilstrup DM, Adson MA (1989) Primary hepatic malignancy: surgical management and determinants of survival. Surgery 106:740–749

    Google Scholar 

  5. Pace RF, Blenkharn JI, Edwards WJ, Orloff M, Blumgart LH, Benjamin IS (1989) Intra-abdominal sepsis after hepatic resection. Ann Surg 209:302–306

    Google Scholar 

  6. Fortner JG, Lincer RM (1990) Hepatic resection in the elderly. Ann Surg 211:141–145

    Google Scholar 

  7. Choi TK, Lai Edward CS, Fan ST, Mok Francis PT, Wong J (1990) Results of surgical resection for hepatocellular carcinoma. Hepatogastroenterology 37:172–175

    Google Scholar 

  8. Yanaga K, Kanematsu T, Takenaka K, Sugimachi K (1986) Intraperitoneal septic complications after hepatectomy. Ann Surg 203:148–152

    Google Scholar 

  9. Grover GJ, Loegering DJ (1982) Effect of splenic sequestration of erythrocytes on splenic clearance function and susceptibility to septic peritonitis. Infect Immun 36:96–102

    Google Scholar 

  10. Tartter PI (1988) Blood transfusion and infectious complications following colorectal cancer surgery. Br J Surg 75:789–792

    Google Scholar 

  11. Galandiuk S, George CD, Pietsch JD, Byck DC, DeWeese RC, Polk HC Jr (1990) An experimental assessment of the effect of blood transfusion on susceptibility to bacterial infection. Surgery 108:567–571

    Google Scholar 

  12. Jensen LS, Andersen A, Fristrup SC, Holme JB, Hvid HM, Kraglund K, Rasmussen PC, Toftgaard C (1990) Comparison of one doses versus three doses of prophylactic antibiotics, and the influence of blood transfusion, on infectious complications in acute and elective colorectal surgery. Br J Surg 77:513–518

    Google Scholar 

  13. Rolando N, Harvey F, Brahm J, Philpott-Howard J, Alexander G, Gimson A, Casewell M, Fagan E, Williams R (1990) Prospective study of bacterial infection in acute liver failure: an analysis of fifty patients. Hepatology 11:49–53

    Google Scholar 

  14. Nsouli KA, Lazarus M, Schoenbaum SC, Gottlieb MN, Lowrie EG, Shocair M (1979) Bacteremic infection in hemodialysis. Arch Intern Med 139:1255–1258

    Google Scholar 

  15. Yamagata M, Kanematsu T, Matsumata T, Nishizaki T, Utsunomiya T, Sugimachi K, Okuda S (1993) Possibility of hepatic resection in patients on maintenance hemodialysis. Hepatogastroenterology 40:249–252

    Google Scholar 

  16. Andersson R, Tranberg KG, Bengmark S (1990) Roles of bile and bacteria in biliary peritonitis. Br J Surg 77:36–39

    Google Scholar 

  17. Nishizaki T, Matsumata T, Yanaga K, Shimada M, Higashi H, Sugimachi K (1993) Open and closed suction drainage after hepatic resection. Surg Today 23:871–874

    Google Scholar 

  18. Raves JJ, Slifkin M, Diamond DL (1984) A bacteriologic study comparing closed suction and simple conduit drainage. Am J Surg 148:618–620

    Google Scholar 

  19. Wells CL, Rotstein OD, Pruett TL, Simmons RL (1986) Intestinal bacteria translocate into experimental intra-abdominal abscesses. Arch Surg 121:102–107

    Google Scholar 

  20. Saadia R, Schein M, MacFarlane C, Boffard KD (1990) Gut barrier function and the surgeon. Br J Surg 77:487–492

    Google Scholar 

  21. Offenbartl K, Bengmark S (1990) Intraabdominal infections and gut origin sepsis. World J Surg 14:191–195

    Google Scholar 

  22. Souba WW, Klimberg VS, Plumley DA, Salloum RM, Flynn TC, Bland KI, Copeland EM (1990) The role of glutamine in maintaining a healthy gut and supporting the metabolic response to injury and infection. J Surg Res 48:383–391

    Google Scholar 

  23. Marshall JC, Christou NV, Horn R, Meakins JL (1988) The microbiology of multiple organ failure: the proximal gastrointestinal tract as an occult reservoir of pathogens. Arch Surg 123:309–315

    Google Scholar 

  24. Page CP (1989) The surgeon and gut maintenance. Am J Surg 158:485–490

    Google Scholar 

  25. Moore FA, Feliciano DV, Andrassy RJ, McArdle AH, Booth FVM, Morgenstein-Wagner TB, Kellum JM, Welling RE, Moore EE (1992) Early enteral feeding, compared with parenteral, reduces postoperative septic complications; the results of a meta-analysis. Ann Surg 216:172–183

    Google Scholar 

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Matsumata, T., Yanaga, K., Shimada, M. et al. Occurrence of intraperitoneal septic complications after hepatic resections between 1985 and 1990. Surg Today 25, 49–54 (1995). https://doi.org/10.1007/BF00309385

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