Abstract
In order to clarify what early ischemic changes are produced by venous interruption in the intestine, intestinal vascular lesions caused by peripheral venous ligation were compared with those caused by arterial ligation in rabbits. With less than 30 min ligation, there were only 4 specimens from a total 13 without injury following venous ligation, whereas there were 7 from a total 11 without injury following arterial ligation. After 30 min venous ligation, both the mucosal and submucosal layers of all 10 speciments were affected, while following arterial ligation, 3 of the 11 specimens showed no histological changes. Moreover, in 3 of the remaining 8 specimens from the latter group, the injury was confined to within the mucosal layer.
Thus, in cases of venous interruption, intestinal injury might be evoked earlier with more severe damage than in cases of arterial interruption.
This is a preview of subscription content, log in via an institution to check access.
References
Boley SJ, Schwarts S, Lash J, Sternhill V (1963) Reversible vascular occlusion of the colon. Surg Gynec Obstet 116:53–60
Marston A, Marcuson RW, Chapman M, Arthur JF (1969) Experimental study of devascularization of the colon. Gut 10:121–130
Mattews JGW, Parks TG (1976) Ischaemic colitis in the experimental animal. Gut 17:671–676
Iwata S (1988) An experimental endoscopic study on intestinal ischemic lesion in dogs with special reference to fluoresence endoscopy (in Japanese with English Abstract) J Jpn Surg Soc 89:1014–1021
Marston A (1986) Vascular disease of the colon. In: Marston A, (ed) Vascular disease of the gut. Edward Arnold, Melbourne, pp 152–173
Marcuson RW, Stewart JO, Marston A (1969) Experimental study of devascularization of the colon. Gut 10:121–130
Park PO, Haglung U, Bulkley GB, Falt K (1990) The sequence of development of intestinal tissue injury after strangulation ischemia and reperfusion. Surgery 107:574–580
Parks DA, Bulkley GB, Granger DN, Hamilton SR, McCord JM (1982) Ischemic injury in the cat small intestine: Role of superoxide radicals. Gastroenterology 82:9–15
Thompson JS, Bragg LE, West WW (1990) Serum enzyme levels during intestinal ischemia. Ann Surg 211:369–373.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Nihei, Z., Hojo, I., Minakuchi, H. et al. An experimental study on intestinal vascular lesions: A comparison between the effects of arterial and venous occlusion in the acute phase. Surg Today 23, 280–282 (1993). https://doi.org/10.1007/BF00309243
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00309243