Abstract
We investigated the production of staphylococcal enterotoxin (SE) with respect to coagulase types by methicillin-resistant Staphylococcus aureus (MRSA). A total of 138 strains of MRSA, which were isolated from clinical materials in the surgical ward between 1983 and 1990, were studied. Coagulase type IV strains produced SE A only, whereas coagulase type II strains were classified into four groups by SE production: SE B producing strains (32.7%), SE C producing strains (29.8%), SE B and C coproducing strains (12.5%), and SE A and C coproducing strains (25.0%). Almost all of the organisms (nine of ten) which were isolated from the feces of patients with MRSA enteritis were SE A and C coproducing strains. The coincidence in time of the prevalence of MRSA enteritis and the isolation SE A and C coproducing strains also demonstrated that these strains caused MRSA enteritis. Although SE C producing strains and SE A and C coproducing strains were simultaneously prevalent in 1990, the former tended to be sensitive while the latter tended to be resistant to minocycline. Considering the variety of antibiotic sensitivity in coagulase type II strains, it is thus considered to be of critical importance for epidemiologic purposes to further characterize isolates by SE typing.
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Hori K, Yura J, Shinagawa N, Sakurai S, Mashita K (1989) Postoperative enterocolitis and the current status of MRSA enterocolitis: The result of a questionnaire survey in Japan (English abstract). Kansensho Zasshi 63:701–707
Isono K, Soeda K, Onoda S (1989) Evaluation of MRSA infection after surgery for esophageal cancer patients (in Japanese). Tumor Infect 1:159–163
Konishi T, Yoshida J, Hirata T, Mori K, Hiraishi M, Idezuki Y, Okuzumi K (1989) Infection by methicillin-resistant Staphylococcus aureus after surgery (English Abstract). Saishin Igaku 44:2499–2509
Takahashi M, Sato Y, Asanuma Y, Narisawa T, Koyama K, Tobita M, Nakagomi O (1989) Experiences of postoperative staphylococcal enteritis caused by methicillin-cephem resistant Staphylococcus aureus (MRSA) and the state of the isolation of MRSA. Nippon Geka Gakkai Zasshi (J Jpn Surg Soc) 90:517–523
Christie CDC, Lynch-Ballard E, Andiman WA (1988) Staphylococcal enterocolitis revisited: cytotoxic properties of Staphylococcus aureus from a neonate with enterocolitis. Pediatr Infect Dis J 7:791–795
Takesue Y, Yokoyama T, Kodama T, Fujimoto M, Okita M, Sewake H, Murakami Y, Imamura Y, Tsumura H (1989) Methicillin-resistant Staphylococcus aureaus in nosocomial infection in the surgical ward and operating room. Hiroshima J Med Sci 38:183–186
Kazal HL (1976) Laboratory diagnosis of food-borne diseases. Ann Clin Lab Sci 6:381–399
Fujii Y (1981) On the renewal of the standard method for MIC measurement. Chemotherapy 29:76–79
Igarashi H, Fujikawa H, Usami H, Kawabata S, Morita T (1984) Purification and characterization of Staphylococcus aureus FRI 1,169 and 587 toxic shock syndrome exotoxins. Infect Immun 44:175–181
Suzui K, Hori K, Ishihara H, Muramoto M, Sakurai S, Mashita K, Ishihara S, Shinagawa Y, Yura J (1990) A conclusion for the cause of MRSA enterocolitis: a clinical and experimental study. Nippon Geka Kansenshou Kenkyuu 2:262–266
Takesue Y, Yokoyama T, Kodama T, Murakami Y, Itaba H (1991) The study of postoperative enteritis caused by methicillin-resistant Staphylococcus aureus in our ward (English abstract). Nippon Geka Kansenshou Kenkyuu 3:214–219
Gutman LH, Idriss ZH, Gehlbach S, Blackmon L (1976) Neonatal staphylococcal enterocolitis: Association with indwelling feeding catheters and S. aureus colonization. J Pediatr 88:836–839
Foster EM, Bergdoll MS (1968) Staphylococcal food poisoning. In: Graham HD (ed) Safety of foods. AVI, Westport, CT pp 159–167
Takesue Y, Yokoyama T, Kodama T, Santou T, Nakamitsu A, Murakami Y, Imamura Y, Miyamoto K, Okita M, Tsumura H, Matsuura Y (1992) Toxin involvement in methicillin-resistant Staphylococcus aureus (MRSA) enteritis in gastroenterological surgery. Gastroenterol Jpn 26:716–720
Chesney PJ, Crass BA, Polyak MB, Wand PJ, Warner TF, Vergeront JM, Davis JP, Tobte RW, Chesney RW, Bergdoll MS (1982) Toxic shock syndrome: Management and long-term sequelae. Ann Intern Med 96:849–855
Crass BA, Bergdoll MS (1986) Toxic involvement in toxic shock syndrome. J Infect Dis 153:918–926
Bergdoll MS, Crass BA, Reiser RF, Robbins RN, Davis JP (1981) A new staphylococcal enterotoxin, enterotoxin F, associated with toxic-shock syndrome. Lancet i:1017–1021
DeAzavedo JCS, Arbuthnott JP (1984) Toxicity of staphylococcal toxic shock syndrome toxin 1 in rabbits. Infect Immun 46:314–317
Parsonnet J, Gillis ZA, Richter AZ, Pier GB (1987) A rabbit model of toxic shock syndrome that uses a constant, subcutaneous infusion of toxic shock syndrome toxin 1. Infect Immun 55:1070–1076
McCollister BD, Kreiswirth BN, Novich RP, Schlievert PM (1990) Production of toxic shock syndrome-like illness in rabbits by Staphylococcus aureus D4508: Association with enterotoxin A. Infect Immun 58:2067–2070
Parsonnet J, Hickman RK, Eardley DD, Pier GB (1985) Induction of human interleukin-1 by toxic-shock-syndrome toxin-1. J Infect Dis 151:514–522
Jupin C, Anderson S, Damais C, Alouf JE, Papant M (1988) Toxic shock syndrome toxin-1 as an inducer of human tumor necrosis factors and γ-interferon. J Exp Med 167:742–761
Beezhold DH, Best GK, Bonventre PF, Thompson M (1987) Synergistic induction of interleukin-1 by endotoxin and toxic shock syndrome toxin-1 using rat macrophages. Infect Immun 55:2865–2869
Ubukata K, Nonoguchi R, Matsuhashi M, Song MD, Konno M (1989) Restriction maps of the regions coding for methicillin and tobramycin resistances on chromosomal DNA in methicillin-resistant Staphylococci. Antimicrob Agents Chemother 33:1624–1629
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Takesue, Y., Yokoyama, T., Kodama, T. et al. A study on postoperative enteritis caused by methicillin-resistant Staphylococcus aureus . Surg Today 23, 4–8 (1993). https://doi.org/10.1007/BF00308992
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DOI: https://doi.org/10.1007/BF00308992