Summary
1. A cytogenetic analysis of 18 independent lz mutants is presented.
2. On a phenotypic basis the mutants can be separated into three classes.
3. The results of a recombination analysis show that each of the 18 mutants can be assigned to one of three loci. No case where a lz mutant involved more than one locus was found.
4. Both phenotypic and recombination evidence place the amx mutant outside the lz pseudoallelic system.
5. Cytologically the lz pseudoalleles have been localized to section 8D of the salivary X chromosome.
6. The relevance of the data presented to the nature of pseudoallelism is discussed.
Similar content being viewed by others
Literature
Anders, G.: Untersuchungen über das pleiotrope Manifestationsmuster der Mutante lozenge-clawless (lz cl) von Drosophila melanogaster. Z. Vererbungslehre 87, 113 (1955).
Andersen, R. C.: A study of the factors affecting fertility of lozenge females of Drosophila melanogaster. Genetics 30, 280 (1945).
Benzer, S.: Fine structure of a genetic region in bacteriophage. Proc. Nat. Acad. Sci. U.S.A. 41, 344 (1955).
Bridges, C. B., and K. C. Brehme: The mutants of Drosophila melanogaster. Carnegie Inst. Publ. 1944, 552.
Demerec, M., I. Bloomstrand and Z. E. Demerec: Evidence of complex loci in Salmonella. Proc. Nat. Acad. Sci. U.S.A. 41, 359 (1955).
Demerec, M., B. P. Kaufmann, U. Fano, E. Sutton and E. R. Sansome: The gene. Cargeegie Inst. Yrbk. 41, 190 (1942).
Goldschmidt, R. B.: The theory of the gene. Cold Spring Harbor Symp. Quant. Biol. 16, 1 (1951).
Theoretical Genetics, pp. 563. Berkeley and Los Angeles: University of California Press 1955.
Gottschewski, G.: Quantitative und qualitative Unterschiede innerhalb einer Allelenreihe bei Drosophila melanogaster. Zool. Anz. Suppl. 9, 104 (1936).
Green, M. M.: Pseudoallelism and the gene concept. Amer. Naturalist 89, 65 (1955).
A further analysis of the forked locus in Drosophila melanogaster. Proc. Nat. Acad. Sci. U.S.A. 42, 73 (1956).
Green, M. M., and K. C. Green: Crossing-over between alleles at the lozenge locus in Drosophila melanogaster. Proc. Nat. Acad. Sci. U.S.A. 35, 586 (1949).
Komai, T.: Semi-allelic genes. Amer. Naturalist 84, 381 (1950).
Komai, T., and T. Takaku: A study of the closely linked genes minature and dusky in Drosophila virilis, with some considerations on allelism of genes. Cytologia (Tokyo) 14, 87 (1949).
Lewis, E. B.: Pseudoallelism and gene evolution. Cold Spring Harbor Symp. Quant. Biol. 16, 159 (1951).
Pseudoallelism and the gene concept. Caryologia (Pisa) 6, Suppl., 100 (1954).
Some aspects of position pseudoallelism. Amer. Naturalist 89, 73 (1955).
Mackendrick, M. E.: Further examples of crossing over between alleles of the w series. Drosophila Information Service 27, 100 (1953).
Novitski, E.: Position of amx. Drosophila Information Service 23, 65 (1949).
Oliver, C. P., and M. M. Green: Heterosis in compounds of lozenge alleles in Drosophila melanogaster. Genetics 29, 331 (1944).
Pontecorvo, G.: The genitical formulation of gene structure and action. Adv. Enzymol. 13, 121 (1952).
Genetical analysis of cell organization. Symposia Soc. Exper. Biol. 6, 218 (1952).
Gene structure and action in relation to heterosis. Proc. Roy. Soc. Lond., Ser. B, 144, 171 (1955).
Pritchard, R. H.: The linear arrangement of a series of alleles of Aspergillus nidulans. Heredity (Lond.) 9, 343 (1955).
Slatis, H. M., and D. A. Willermet: The miniature complex in Drosophila melanogaster. Genetics 39, 49 (1954).
Stadler, L. J.: The gene. Science (Lancaster, Pa.) 120, 811 (1954).
Stephens, S. G.: Possible significance of duplication in evolution. Adv. Genet. 4, 247 (1951).
Symposium on pseudoallelism and the theory of the gene. Summary, synthesis and critique. Amer. Naturalist 89, 117 (1955).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Green, M.M., Green, K.C. A cytogenetic analysis of the lozenge pseudoalleles in drosophila. Z.Ver-erbungslehre 87, 708–721 (1956). https://doi.org/10.1007/BF00308505
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00308505