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Die Feinstruktur der Gallenblase und der Gallengänge

On the fine structure of gall bladder and biliary ducts

II. Das Epithel der extraphepatischen Gallengänge der Maus und der Ratte

Summary

Fine structures of the ductus hepaticus communis, ductus cysticus and ductus choledochus of mice as well as of the ductus hepatici and ductus choledochus of rats have been investigated.

In the ductus hepaticus communis and ductus cysticus of the mouse there are cells that are similar to the principal cells of the gall bladder epithelium. In addition both these ducts and especially the ductus choledochus contain cells with mucigen granules. There are three further cell types, irregularly distributed in the epithelium of the three ducts: brush cells, goblet cells and basal granulated cells. Macrophages (wandering cells) are present in epithelia.

In the ductus hepatici of the rat the epithelial cells are displaying fine structures similar to those of the ductus hepaticus of the mouse. The ductus choledochus however presents cells with many filaments and desmosomes. Again between these cells there are macrophages, brush cells, goblet cells and basal granulated cells.

The differences in the fine structure of the epithelium of the ductus choledochus of mouse and rat are discussed.

Zusammenfassung

Die Feinstruktur des Ductus hepaticus communis, des Ductus cysticus und des Ductus choledochus der Maus sowie der Ductus hepatici und des Ductus choledochus der Ratte werden untersucht.

Im Ductus hepaticus communis und im Ductus cysticus der Maus kommen Zellen vor, die den Hauptzellen der Gallenblase vergleichbar sind. Außerdem sind in beiden Ductus und vorwiegend im Ductus choledochus neutrale Mukosubstanzen sezernierende Zellen sowie Wanderzellen, Bürstenzellen, Becherzellen und basalgekörnte Zellen vorhanden. Die letztgenannten drei Zelltypen befinden sich nur in einigen Abschnitten der untersuchten Gänge.

Die Feinstrukturen des Epithels der Ductus hepatici der Ratte ähneln jenen des Epithels des Ductus hepaticus der Maus. Der Ductus choledochus enthält dagegen vorwiegend Zellen, die reich an Filamenten und Desmosomen sind. Auch bei der Ratte sind Wanderzellen, Bürstenzellen, Becherzellen und basalgekörnte Zellen festzustellen.

Die unterschiedliche Struktur des Ductus choledochus von Maus und Ratte wird diskutiert.

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Herrn Prof. Dr. H. Ruska danke ich für die wertvolle Diskussion des Manuskriptes.

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Luciano, L. Die Feinstruktur der Gallenblase und der Gallengänge. Z.Zellforsch 135, 103–114 (1972). https://doi.org/10.1007/BF00307091

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Key words

  • Extrahepatic biliary ducts
  • Mouse, rat
  • Epithelial cell types
  • Comparative cytology
  • Light- and electron microscopy