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Composite cerebral metastasis and oligodendroglioma: an exceptional form of mixed neoplasia

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Our report describes the uncommon case of a 61 year old female patient who underwent a left parietooccipital craniotomy and extirpation of a malignant tumor. Histological examination revealed a metastatic carcinoma of mammary origin intimately intermingled with a calcified oligodendroglioma WHO II. The preexisting oligodendroglial part had been detected four years before, but since then had been misinterpreted as a glious scar resulting from a previous brain trauma. Three years before neurosurgical intervention, the patient had undergone a left side mastectomy. The histological finding at that time was a solid breast tumour WHO T1N0. The occurence of cerebral mixed neoplasias and possible causal factors are discussed.

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Wurm, G., Huber, A., Hiertz, H. et al. Composite cerebral metastasis and oligodendroglioma: an exceptional form of mixed neoplasia. Neurosurg. Rev. 17, 291–294 (1994).

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