Summary
Two types of capillaries were found in the medial terminal nucleus of the rat accessory optic system. Type one capillaries are surrounded by glial processes and lack a perivascular space, whereas the type two capillaries and arterioles show a distinct extracellular perivascular space often filled with collagen fibrils. An internal as well as an external basal lamina lines these spaces. No fenestration of the endothelium was observed.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Andres, K. H.: Der Feinbau des Subfornikalorgans vom Hund. Z. Zellforsch. 68, 445–473 (1965).
Dempsey, E. W., Wislocki, G. B.: An electron microscopic study of the blood-brain barrier in the rat, employing silver nitrate as a vital stain. J. biophys. biochem. Cytol. 1, 245–256 (1955).
Dobbing, J.: The blood-brain barrier. Physiol. Rev. 41, 130–188 (1961).
Farquhar, M. G., Hartmann, J. F.: Neuroglial structure and relationships as revealed by electron microscopy. J. Neuropath. exp. Neurol. 16, 18–39 (1957).
Hartmann, J. F.: Electron microscopy of the neurophyophysis in normal and histamine-treated rats. Z. Zellforsch. 48, 291–308 (1958).
Hayhow, W. R., Webb, C., Jervie, A.: The accessory optic fiber system in the rat. J. comp. Neurol. 115, 187–215 (1960).
Herrlinger, H.: Licht- und elektronenmikroskopische Untersuchungen am Subcommissuralorgan der Maus. Ergebn. Anat. Entwickl.-Gesch. 42, 7–73 (1970).
Hirano, A.: The fine structure of brain in edema. In: The structure and function of nervous tissue, vol. II. Structure II and physiology. New York and London: Academic Press, 1969.
Holmes, R. L.: The infundibular process of rodents in the genus Meriones. Z. Zellforsch. 85, 256–263 (1968).
Leonhardt, H.: Über die Blutkapillaren und perivaskulären Strukturen der Area postrema des Kaninchens und über ihr Verhalten im Pentamethylentetrazol-(„Cardiazol“-) Krampf. Z. Zellforsch. 76, 511–524 (1967).
Maynard, E. A., Schultz, R. L., Pease, D. C.: Electron microscopy of the vascular bed of rat cerebral cortex. Amer. J. Anat. 100, 409–433 (1957).
Moore, R., Heller, A., Wurtman, R., Axelrod, J.: Visual pathway mediating pineal response to environmental light. Science 155, 220–223 (1967).
Papacharalampous, N. X., Schwink, A., Wetzstein, R.: Elektronenmikroskopische Untersuchungen am Subcommissuralorgan des Meerschweinchens. Z. Zellforsch. 90, 202–229 (1968).
Rohr, V. U.: Zum Feinbau des Subfornikal-Organs der Katze. I. Der Gefäß-Apparat. Z. Zellforsch. 73, 246–271 (1966).
Rudert, H., Schwink, A., Wetzstein, R.: Feinstruktur des Subfornikalorgans beim Kaninchen. I. Die Blutgefäße. Z. Zellforsch. 74, 252–270 (1966).
Schmidt, W. R., D'Agostino, A. N.: The subcommissural organ of the adult rabbit. Neurology 16, 373–379 (1966).
Schwink, A., Wetzstein, R.: Die Kapillaren im Subcommissuralorgan der Ratte. Elektronenmikroskopische Untersuchungen an Tieren verschiedenen Lebensalters. Z. Zellforsch. 73, 56–88 (1966).
Scott, D. E., Knigge, K. M.: Ultrastructural changes in the median eminence of the rat following deafferentation of the basal hypothalamus. Z. Zellforsch. 105, 1–32 (1970).
Shimizu, N., Ishii, S.: Fine structure of the area postrema of the rabbit brain. Z. Zellforsch. 64, 462–473 (1964).
Stanka, P., Schwink, A., Wetzstein, R.: Elektronenmikroskopische Untersuchung des Subcommissuralorgans der Ratte. Z. Zellforsch. 63, 277–301 (1964).
Venable, J. H., Coggeshall, R.: A simplified lead citrate stain for use in electron microscopy. J. Cell Biol. 25, 407–408 (1965).
Weindl, A.: Zur Morphologie und Histochemie von Subfornicalorgan, Organum vasculosum laminae terminalis und Area postrema bei Kaninchen und Ratte. Z. Zellforsch. 67, 740–775 (1965).
— Schwink, A., Wetzstein, R.: Der Feinbau des Gefäßorgans der Lamina terminalis beim Kaninchen. I. Die Gefäße. Z. Zellforsch. 79, 1–48 (1967).
Wetzstein, R., Papacharalampous, N. X., Schwink, A.: Kollagen in der Basalmembran subcommissuraler Kapillaren des Meerschweinchens. Naturwissenschaften 53, 283 (1966).
— Schwink, A., Stanka, P.: Die periodisch strukturierten Körper im Subcommissuralorgar der Ratte. Z. Zellforsch. 61, 493–523 (1963).
Wolff, J.: Beiträge zur Ultrastruktur der Kapillaren in der normalen Großhirnrinde, Z. Zellforsch. 60, 409–431 (1963).
— Über die Möglichkeiten der Kapillarverengung im Zentralnervensystem. Eine elektronenmikroskopische Studie an der Großhirnrinde des Kaninchens. Z. Zellforsch. 63, 593–611 (1964).
Wong, M. T. T.: Somato-dendritic and dendro-dendritic synapses in the squirrel monkey lateral geniculate nucleus. Brain Res. 20, 135–139 (1970).
Wyckoff, R. W. G., Young, J. Z.: The motorneuron surface. Proc. roy. Soc. B 144, 440–450 (1956).
Author information
Authors and Affiliations
Additional information
This study was supported by N. I. H. Grant RR-00165 to Yerkes Regional Primate Research Center, and N. I. H. Grants R01-EY 00565-03 and R01-EY 00638-02 to J. Tigges. The excellent technical assistance of Mrs. G. L. Luttrell is gratefully acknowledged. We thank Dr. W. K. O'Steen for providing the rats and Mr. F. H. Kiernan for photographic help. Special thanks are due to Mrs. B. A. Olberding, in charge of the maintenance of the electron microscope.
Rights and permissions
About this article
Cite this article
Tigges, M., Tigges, J. Extracellular perivascular connective tissue space in the medial terminal nucleus of the accessory optic system in rats. Z.Zellforsch 125, 289–294 (1972). https://doi.org/10.1007/BF00306627
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00306627