Summary
Nerve fibers containing granular vesicles and vesicles closely resembling synaptic vesicles appear in the median eminence of 14 days old mouse fetuses. At 18th fetal day true nerve endings have been observed which are located close to the capillaries of the superficial plexus forming a neurovascular link. The capillary loops penetrate into the median eminence at the time of parturition but only in 5 days old mice they can be observed more frequently. — On the basis of the morphological observations presented the question is discussed whether the hypothalamus can influence pituitary hormone secretion before birth.
Résumé
Les fibres nerveuses renfermant des vésicules granuleuses et des vésicules de type synaptique apparaissent dans l'éminence médiane de foetus de 14 jours. Dés le 18è jour foetal, de véritables terminaisons nerveuses sont au contact des capillaires du plexus intercalaire, constituant une charnière neurohémale. Les anses intrainfundibulaires commencent à pénétrer dans l'éminence médiane à la naissance mais ce n'est que chez des souris de 5 jours qu'elles deviennent très nombreuses. — Nous discuterons sur des critères morphologiques, de la possibilité d'un contrôle hypothalamique sur l'adénohypophyse avant la naissance.
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Akmayev, I. G., Rethelyi, M., Majorossy, K.: Changes induced by adrenalectomy in nerve endings of the hypothalamic median eminence (Zona palisadica) in the albino rat. Acta biol. Acad. Sci. hung. 18, 187–200 (1967).
Barry, J., Cotte, G.: Etude préliminaire au microscope électronique de l'éminence médiane du cobaye. Z. Zellforsch. 53, 714–724 (1961).
Beauvillain, J.-C.: Structure fine de l'éminence médiane de la souris. Etude chez l'adulte et au cours de l'ontogénèse. Thèse de 3è cycle Université de Lille (1972).
Bergland, R. M., Torack, R. M.: An electron microscopic study of the human infundibulum. Z. Zellforsch. 99, 1–12 (1969).
Björklund, A., Enemar, A., Falck, B.: Monoamines in the hypothalamo-hypophyseal system of the mouse with special reference to the ontogenetic aspects. Z. Zellforsch. 89, 590–607 (1968).
Campbell, M. J.: The development of the primary portal plexus in the median eminence of the rabbit. J. Anat. (Lond.) 100, 381–387 (1966).
Daikoku, S., Morishita, M., Hashimoto, T., Takamashi, A.: Light microscopic studies on the development of the interrelationship between the neurosecretory pathway and the portal system in rats. Endocr. jap. 14, 209–224 (1967).
Daikoku, S., Sato, T. J. A., Hashimoto, T., Morishita, M., Development of the ultrastructures of the median eminence and supraoptic nuclei in rats. Tokushima J. exp. Med. 15, 1–2 (1968).
Enemar, A.: The structure and development of the hypophyseal portal system in the laboratory mouse, with particular regard to the primary plexus. Arch. Zool. 13, 203–252 (1961).
Eurenius, L., Jarskär, R.: Electron microscopic studies on the development of the external zone of the mouse median eminence. Z. Zellforsch. 122, 488–502 (1971).
Falck, B., Hillarp, N. A., Thieme, G., Thorp, A.: Fluorescence of catecholamines and related compounds condensed with formaldehyde. J. Histochem. Cytochem. 10, 348–354 (1962).
Fink, G., Smith, G. C.: Ultrastructural features of the development of the hypothalamopituitary axis in the rat. J. Anat. (Lond.) 108, 207 (1971a).
Fink, G., Smith, G. C.: Ultrastructural features of the developing hypothalamo-hypophysial axis in the rat. A correlation study. Z. Zellforsch. 119, 208–226 (1971b).
Fuxe, K.: Cellular localization of monomamines in the median eminence and infundibular stem of some mammals. Z. Zellforsch. 61, 710–724 (1964).
Glydon, R. St. J.: The development of the blood supply of the pituitary in the albino rat with special reference to the portal vessels. J. Anat. (Lond.) 91, 237–244 (1957).
Halasz, B., Kosaras, B., Lengvari, I.: Ontogenesis of the neurovascular link between the hypothalamus and the anterior pituitary in the rat. In: Brain-Endocrine Interaction. Median Eminence; Structure and Function. Int. Symp. Munich 1971, p. 27–34. Basel: Karger 1972.
Herlant, M., de Busscher, A., Laloux, G.: Etude au microscope électronique de l'action de la réserpine sur le système tubéro-hypophysaire chez la souris. C. R. Sc. Nat. 270, 2689–2691 (1970).
Hyyppä, M.: A histochemical study of the primary catecholamines in the hypothalamic neurons of the rat in relation to the ontogenic and sexual differentiation. Z. Zellforsch. 98, 550–560 (1969).
Ishii, S.: Classification and identification of neurosecretory granules in the median eminence. In: Brain-Endocrine Interaction. Median Eminence: Structure and Function, Int. Symp. Munich 1971, p. 119–141. Basel: Karger 1972.
Jost, A., Dupouy, J.-P., Gelaso-Meyer, A.: Hypothalamo-hypophyseal relationships in the fetus. In: Martini, Motta, Fraschini, The hypothalamus, p. 605–615. New York: Academic Press 1970.
Karnovsky, M.: A formaldehyde glutaraldehyde fixative of high osmolarity for use in electron microscopy. J. Cell Biol. 27, 137A (1965).
Kobayashi, T., Kobayashi, T., Yamamoto, K., Inatomi, M.: Electron microscopy observations of the hypothalamo-hypophyseal system of the rat. Endocr. jap. 10, 69–80 (1963).
Kobayashi, T., Kobayashi, T., Yamamoto, K., Kaibara, M., Ajika, K.: Electron microscopic observations on the hypothalamo-hypophyseal system in rats. Ultrafine structure of the developing median eminence. Endocr. jap. 15, 337–363 (1968).
Loizou, L. A.: The postnatal development of monoamine containing structures in the hypothalamo-hypophyseal system of the albino rat. Z. Zellforsch. 114, 234–252 (1971).
Matsui, T.: Effect of reserpine on the distribution of granulated vesicles in the mouse median eminence. Neuroendocrinology 2, 99–106 (1967).
Mazzuca, M.: Structure fine de l'éminence médiane du cobaye. J. Microscop. 4, 225–238 (1965).
Monroe, B. G.: A comparative study of the ultrastructure of the median eminence, infundibular stem and neural lobe of the hypophysis of the rat. Z. Zellforsch. 76, 405–432 (1967).
Monroe, B. G., Newman, B. L., Schapiro, S.: Ultrastructure of the median eminence of neonatal and adult rats. In: Brain-Endocrine Interaction. Median Eminence: Structure and Function, Int. Symp. Munich 1971, p. 7–26. Basel: Karger 1972.
Oota, Y.: Fine structure of the median eminence and the pars nervosa of the mouse. J. Fac. Scien. Tokyo. 10, 155–168 (1963).
Oota, Y., Kawabata, I., Kurosumi, K.: Electron microscopic studies on the rat hypothalamo-hypophyseal neurosecretory system. Jap. J. exp. Morph. 20, 65–83 (1966).
Richardson, K. C., Jarett, L., Finke, E. H.: Note on the use of araldite epoxy resins for ultrathin sectioning in electron microscopy. Stain Technol. 35, 313–323 (1960).
Rinne, U. K.: Ultrastructure of the median eminence of the rat. Z. Zellforsch. 74, 98–122 (1966).
Röhlich, P., Vigh, B., Teichmann, I., Aros, B.: Electron microscopy of the median eminence of the rat. Acta biol. Acad. Sci. hung. 15, 431–457 (1965).
Smith, G. C.: Ultrastructural studies on the median eminence of neonatal rats. J. Anat. (Lond.) 106, 200 (1970).
Smith, G. C., Simpson, R. W.: Monoamine fluorescence in the median eminence of the foetal, neonatal and adult rats. Z. Zellforsch. 104, 541–556 (1970).
Terneby, U. K.: The development of the hypophysial vascular system in the rabbit, with particular regard to the primary plexus and portal vessels. J. of Neuro-Visceral Relations 32, 311–346 (1972).
Venable, J. H., Coggeshall, R.: A simplified lead citrate stain for use in electron microscopy. J. Cell Biol. 25, 407–408 (1965).
Zambrano, D., de Robertis, E.: The effect of castration upon the ultrastructure of the rat hypothalamus. II. Arcuate nucleus and outer zone of the median eminence. Z. Zellforsch. 87, 409–421 (1968).
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Beauvillain, JC. Structure fine de l'eminence médiane de souris au cours de son ontogenese. Z.Zellforsch 139, 201–215 (1973). https://doi.org/10.1007/BF00306522
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DOI: https://doi.org/10.1007/BF00306522