Summary
The innervation pattern of rat and mouse inferior vena cava was studied using catecholamine fluorescence and cholinesterase histochemical methods.
Adrenergic nerve fibers innervate only abdominal protions of the inferior vena cava, while cholinergic nerves are chiefly distributed to the thoracic inferior vena cava and show a gradual decrease in the abdomen.
Chemical sympathectomy performed with the neurotoxin 6-hydroxydopamine does not alter the pattern of cholinergic innervation of the inferior vena cava, suggesting the parasympathetic nature of cholinergic nerves.
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Amenta F, Porcelli F, Ferrante F (1979) Histochemical studies on the autonomic innervation of the femoral artery and vein. Anat Embryol 157:231–235
Bevan JA, Hosmer DW, Ljung B, Pegram BL, Su C (1974) Innervation pattern and neurogenic response of rabbit veins. Blood Vessels 11:172–182
Burnstock G, Chamley JH, Campbell GR (1980) The innervation of arteries. In: Schwartz CJ, Werthessen NT, Wolf S (eds) Structure and function of circulation. Vol 10. Plenum Press, New York
Falck B (1962) Observations on the possibilities of the cellular localization of monoamines by a fluorescence method. Acta Physiol Scand 197:Suppl 56:1–25
Hamilton WJ, Boyd JD, Mossman HW (1972) Human embryology. Heffer, Cambridge
Ichikawa T, Ishikawa N, Shigei T (1979) Innervation of the canine inferior vena cava. Distribution of adrenergic and cholinergic excitatory fibers among the embriologically distinct segment. Blood Vessels 16:155–162
Jonsson G (1980) Chemical neurotoxins as denervation tools in neurobiology. Ann Rev Neurosc 3:169–187
Pegram BL, Bevan JA, Ljung B, Su C (1973) The neuromuscular mechanism of vein. Proc West Pharm Soc 1:49–52
Shigei T, Ishikawa N, Ichikawa T, Tsuru H (1978) Differences in the response of three embriologically distinct segment of the isolated inferior vena cava to vasoactive substance. Blood Vessels 15:157–169
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Amenta, F., Cantagalli, A., Cavallotti, C. et al. Innervation pattern of inferior vena cava in mouse and rat. Anat Embryol 165, 233–238 (1982). https://doi.org/10.1007/BF00305479
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DOI: https://doi.org/10.1007/BF00305479