Summary
The development of the catecholamine-specific fluorescence in the pigment epithelium of the guinea-pig eye during fetal life is investigated. At the 16th day of gestation a specific fluorescence in the outer layer of the optic cup can be demonstrated. It disappears with the onset of melanin synthesis in the pigment cells, while the fluorescence in the pigment epithelium of albinotic animals persists until birth and has its maximun intensity at the 40th day of gestation. The fluorescence is considered to be Dopa-specific.
Zusammenfassung
Es wird über die Entwicklung einer katecholamin-spezifischen Fluorescenz im Pigmentepithel des Meerschweinchenauges während der Embryonalzeit berichtet. Ab 16. Tragtag ist mit der Methode der „formaldehyde-induced fluorescence“ am Kryostatschnitt eine spezifische Fluorescenz in den Zellen der äußeren Lamelle des Augenbechers nachweisbar. Während die Fluorescenz bei pigmentierten Tieren mit dem Auftreten von Melanin am Ort der Melaninablagerung verschwindet, bleibt sie bei Albinos bis zur Geburt erhalten und erreicht hier bis zum 40. Tag der Embryonalentwicklung ihr Maximum. Es kann angenommen werden, daß wir durch die Fluorescenz Dopa erfassen.
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Winckler, J., Turner, H.B. Über das Vorkommen von Katecholaminen im Pigmentepithel des Meerschweinchenauges während der Entwicklung. Histochemie 19, 272–280 (1969). https://doi.org/10.1007/BF00305290
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DOI: https://doi.org/10.1007/BF00305290