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Early testicular development in sex reversed mice

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Summary

A comparison is made of two sets of data bearing on the development of testes in XX, Sxr mice. Although Spoljar and Drews (1978) reported no significant difference in the growth rates of XX and XY testes, nevertheless their data suggest that such a difference may exist. This confirms earlier work by Mittwoch and Buehr (1973), who found the testicular volumes of XX embryos aged 15 and 16 days to be below those of XY embryos.

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References

  • Cattanach, B.M., Pollard, C.E., Hawkes, S.G.: Sex reversed mice: XX and X0 males. Cytogenetics 10, 318–337 (1971)

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  • Mittwoch, U., Buehr, M.L.: Gonadal growth in embryos of Sex reversed mice. Differentiation 1, 219–224 (1973)

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  • Spoljar, M.: Untersuchungen zur Wirkungsweise der “Sex Reversed” Mutation bei der Maus: Die histologische Entwicklung der Gonadenanlage in geschlechtsumgekehrten X/X-Männchen. Inaugural-Dissertation, Ulm (1975)

  • Spoljar, M., Drews, U.: Identical action of Y chromosome and Sxr factor in early testicular development in the mouse. Anat. Embryol. (Berl.) 155, 115–126 (1978)

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Mittwoch, U. Early testicular development in sex reversed mice. Anat Embryol 157, 177–179 (1979). https://doi.org/10.1007/BF00305158

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  • DOI: https://doi.org/10.1007/BF00305158

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