Skip to main content
Log in

Cerebellar cortical and nuclear afferents from the Edinger-Westphal nucleus in the cat

  • Original Articles
  • Published:
Anatomy and Embryology Aims and scope Submit manuscript

Summary

The cerebellar projection from the Edinger-Westphal nucleus was studied in the cat by means of retrograde transport of the wheat germ agglutinin-horseradish peroxidase complex. The present findings give evidence that the flocculus is the main terminal area. However, small tracer implants and injections into various parts of the cerebellar nuclei and cortex revealed projections also to the fastigial and interposed nuclei and to most parts of the anterior and posterior lobe cortices. The projecting neurons are small and located bilaterally throughout the Edinger-Westphal nucleus. No topical differences between the projections to different parts of the cerebellum were found.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Aschoff A, Holländer H (1982) Fluorescent compounds as retrograde tracers compared with horseradish peroxidase (HRP). I. A parametric study in the central visual system of the albino rat. J Neurosci Methods 6:179–197

    Google Scholar 

  • Brodal A (1981) Neurological anatomy in relation to clinical medicine. Oxford University Press, New York London

    Google Scholar 

  • Brodal P, Dietrichs E, Bjaalie JG, Nordby T, Walberg F (1983) Is lectin-coupled horseradish peroxidase taken up and transported by undamaged as well as by damaged fibres in the central nervous system? Brain Res 278:1–9

    Google Scholar 

  • Cohen D, Chambers W, Sprague JM (1958) Experimental study of the efferent projections from the cerebellar nuclei to the brainstem of the cat. J Comp Neurol 109:233–259

    Google Scholar 

  • Dietrichs E, Walberg F (1983) Cerebellar cortical afferents from the red nucleus in the cat. Exp Brain Res 50:353–358

    Google Scholar 

  • Dietrichs E, Walberg F (1986) The cerebellar nucleo-olivary and olivocerebellar nuclear projections in the cat as studied with anterograde and retrograde transport in the same animal after implantation of crystalline WGA-HRP. III. The interposed nuclei. Brain Res 373:373–383

    Google Scholar 

  • Dietrichs E, Walberg F (1987) Cerebellar nuclear afferents-where do they originate? A re-evaluation of the projections from some lower brain stem nuclei. Anat Embryol 177:165–172

    Google Scholar 

  • Dietrichs E, Walberg F, Nordby T (1985) The cerebellar nuclcoolivary and olivo-cerebellar nuclear projections in the cat as studied with anterograde and retrograde transport in the same animal after implantation of crystalline WGA-HRP. I. The dentate nucleus. Neurosci Res 3:52–70

    Google Scholar 

  • Gibson AR, Hansma DI, Houk JC, Robinson FR (1984) A sensitive low artifact TMB procedure for the demonstration of WGA-HRP in the CNS. Brain Res 298:235–241

    Google Scholar 

  • Hosoba M, Bando T, Tsukahara N (1978) The cerebellar control of accomodation of the eye in the cat. Brain Res 153:495–505

    Google Scholar 

  • Hultborn H, Mori K, Tsukahara N (1978) Cerebellar influence on parasympathetic neurones innervating intra-ocular muscles Brain Res 159:269–278

    Google Scholar 

  • Ito M (1984) The cerebellum and neural control. Raven Press, New York

    Google Scholar 

  • Larsell O (1970) The comparative anatomy and histology of the cerebellum from monotremes through apes. Jansen J (Ed) University of Minnesota Press, Minneapolis

    Google Scholar 

  • Loewy AD, Saper CB (1978) Edinger-Westphal nucleus: Projections to the brain stem and spinal cord in the cat. Brain Res 150:1–27

    Google Scholar 

  • Loewy AD, Saper CB, Yamodis ND (1978) Re-evaluation of the efferent projections of the Edinger-Westphal nucleus in the cat. Brain Res 141:153–159

    Google Scholar 

  • Maciewicz R, Phipps BS, Foote WE, Aronin N, DiFiglia M (1983) The distribution of substance P-containing neurons in the cat Edinger-Westphal nucleus: Relationship to efferent projection systems. Brain Res 270:217–230

    Google Scholar 

  • Mesulam M-M (1978) Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: A non-carcinogenic blue reaction-product with superior sensitivity for visualizing neural afferents and efferents. J Histochem Cytochem 26:106–117

    Google Scholar 

  • Mori J, Hori N, Katsuda N (1981) A new method for application of horseradish peroxidase into a restricted area of the brain. Brain Res Bull 6:19–22

    Google Scholar 

  • Pugh WW, Kalia M (1982) Differential uptake of peroxidase (HRP) and peroxidase-lectin (HRP-WGA) conjucate injected in the nodose ganglion of the cat. J Histochem Cytochem 30:887–894

    Google Scholar 

  • Qvist H, Dietrichs E (1986) Afferents to the lateral reticular nucleus from the oculomotor region. I. The Edinger-Westphal nucleus. Anat Embryol 175:261–269

    Google Scholar 

  • Saint-Cyr JA (1983) The projection from the motor cortex to the inferior olive in the cat. An experimental study using axonal transport techniques. Neuroscience 10:667–684

    Google Scholar 

  • Sekiya H, Kawamura K, Ishikawa S (1984) Projections from the Edinger-Westphal complex of monkeys as studied by means of retrograde axonal transport of horseradish peroxidase. Arch Ital Biol 122:311–319

    Google Scholar 

  • Sugimoto T, Itoh K, Mizuno N (1977) Localization of neurons giving rise to the oculomotor parasympathetic outflow: A HRP study in the cat. Neurosci Lett 7:301–305

    Google Scholar 

  • Sugimoto T, Itoh K, Mizuno N (1978) Direct projections from the Edinger-Westphal nucleus to the cerebellum and spinal cord in the cat: An HRP study. Neurosci Lett 9:17–22

    Google Scholar 

  • Thomas DM, Kaufman RP, Sprague JM, Chambers WW (1956) Experimental studies of the vermal cerebellar projections in the brain stem of the cat (fastigiobulbar tract). J Anat 90:371–385

    Google Scholar 

  • Toyoshima K, Kawana E, Sakai H (1980) On the neuronal origin of the afferents to the ciliary ganglion in cat. Brain Res 185:67–76

    Google Scholar 

  • Walberg F (1982) The origin of olivary afferents from the central grey and its surroundings in the cat. Anat Embryol 164:139–151

    Google Scholar 

  • Walberg F, Nordby T, Dietrichs E (1980) A note on the anterograde transport of horseradish peroxidase within the olivocerebellar fibres. Exp Brain Res 40:233–236

    Google Scholar 

  • Walberg F, Nordby T, Dietrichs E (1987) The olivonodular projection: A re-examination based on folial cerebellar implants. Neurosci Lett 81:82–88

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Røste, G.K., Dietrichs, E. Cerebellar cortical and nuclear afferents from the Edinger-Westphal nucleus in the cat. Anat Embryol 178, 59–65 (1988). https://doi.org/10.1007/BF00305015

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00305015

Key words

Navigation