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Principal components analysis as an aid to classification of renal dynamic studies

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Abstract

Four hundred renal dynamic studies obtained using 99mTc-(Sn) DTPA were classified clinically into four classes (normal, pre-renal lesion, intrarenal lesion and urinary tract obstruction). Principal components analysis was then applied to the kidney activity/time curves and yielded good class separation using only three components. The separation of normal and obstructed or damaged kidneys using only the first component was better than that obtained using the calculated mean transit time.

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Houston, A.S., Macleod, M.A. & Sampson, W.F.D. Principal components analysis as an aid to classification of renal dynamic studies. Eur J Nucl Med 4, 295–299 (1979). https://doi.org/10.1007/BF00304888

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