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VP-16, ifosfamide, and methotrexate combination chemotherapy for aggressive non-Hodgkin's lymphomas after failure of the LNH 84 regimen

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  • VP-16, Ifosfamide, Methotrexate, Non-Hodgkin's Lymphoma, LNH 84
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Summary

A total of 20 patients with intermediate or highgrade non-Hodgkin's lymphomas who failed to LNH 84 regimen were treated with a combination of VP 16, ifosfamide and methotrexate (VIM regimen). Nineteen patients are evaluable for response. Eight patients (42%) achieved complete responses and four (21%) attained partial responses. Most of the complete responders are still in remission with a follow-up of more than 30 months for 5 patients.

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References

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Authors and Affiliations

  1. Service d'Onco-Hématologie, Hôpital de Hautepierre, F-67098, Strasbourg, France

    R. Herbrecht, J. J. Garcia, J. P. Bergerat, P. Dufour, B. Duclos & F. Oberling

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  1. R. Herbrecht
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  2. J. J. Garcia
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  3. J. P. Bergerat
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  4. P. Dufour
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  5. B. Duclos
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  6. F. Oberling
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Herbrecht, R., Garcia, J.J., Bergerat, J.P. et al. VP-16, ifosfamide, and methotrexate combination chemotherapy for aggressive non-Hodgkin's lymphomas after failure of the LNH 84 regimen. Cancer Chemother. Pharmacol. 24, 338–339 (1989). https://doi.org/10.1007/BF00304770

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  • DOI: https://doi.org/10.1007/BF00304770

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