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Topographic organization of the auditory thalamocortical system in the albino rat

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Summary

The organization of the auditory thalamocortical connections was studied in rats. Retrograde transport of horseradish peroxidase conjugated to wheat germ agglutinin following injections into parietal, occipital and temporal cortex was used. The medial geniculate body, the suprageniculate, the lateral part of the nucleus posterior thalami, the posterior part of the nucleus lateralis thalami, and the nucleus ventroposterior project to the investigated part of the neocortex. Corresponding to different patterns of labeling, five areas of auditory neocortex were distinguished: 1. The rostral area is innervated by neurons of the nucleus ventroposterior, the lateral part of the nucleus posterior thalami, and the medial division of the medial geniculate body. 2. The dorsal area is innervated by neurons of the suprageniculate, the posterior part of the nucleus lateralis thalami and the rostral region of the dorsal division of the medial geniculate body. 3. The caudal area is innervated by neurons of the posterior part of the nucleus lateralis thalami, the suprageniculate, the medial division, the caudal region of the dorsal division and the ventrolateral nucleus of the medial geniculate body. 4. The ventral area is innervated by neurons of the suprageniculate, the medial division, the caudal region of the dorsal division, and the ventrolateral nucleus of the medial geniculate body. 5. The core area of the temporal cortex is exclusively connected to the caudal region of the medial division and the ventral division of the medial geniculate body.

The findings of the present study indicate topographic organizations of the ventral division of the medial geniculate body and of the corea area. Four segments (a-d) of the ventral division each show a different set of topographic axes. They correspond to sets of topographic axes in the core area of the auditory cortex. These topographies characterize the segments which are each exclusively connected to one of the four fields of the core area.

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Abbreviations

AC :

Auditory Cortex

c :

Caudal

d :

Dorsal

FR :

Fissura rhinalis, Rhinal Fissure

l :

Lateral

LTP :

Nucleus lateralis thalami, pars posterior

m :

Medial

MGB :

Medial geniculate body

MGBd :

Medial geniculate body, dorsal division

MGBm :

Medial geniculate body, medial division

MGBmc :

Medial geniculate body, caudal third of MGBm

MGBv :

Medial geniculate body, ventral division

MGBvl :

Medial geniculate body, ventrolateral nucleus

NPT :

Nucleus posterior thalami, pars lateralis

r :

Rostral

SG :

Suprageniculatum

VP :

Nucleus ventroposterior

References

  • Andersen RA, Snyder RL, Merzenich MM (1980) The topographic organization of corticocollicular projections from physiologically identified loci in the AI, AIl, and Anterior Auditory Fields of the cat. J Comp Neurol 191:479–494

    Google Scholar 

  • Cheff SJ, Larue DT, Winer JA (1987) The rat medial geniculate complex: Nuclear architecture, neuronal organization, and neocortical connections. Neurosci [Abstr] 13:151.8

    Google Scholar 

  • Cipolloni PB, Peters A (1979) The bilaminar and banded distribution of the callosal terminals in the posterior neocortex of the rat. Brain Res 176:33–47

    Google Scholar 

  • Clerici WJ, Maxwell B, Byrd DR, Coleman JR (1987) Development of the rat medial geniculate body: Quantification of neurons in the ventral division. Neurosci [Abstr] 13:90.3

    Google Scholar 

  • Coleman J, Clerici WJ (1980) Extrastriate projections from thalamus to posterior occipital-temporal cortex in rat. Brain Res 194:205–209

    Google Scholar 

  • Colwell SA, Merzenich MM (1975) Organization of thalamocortical and corticothalamic projections to and from physiologically defined loci within primary auditory cortex in the cat. Anat Rec 181:336

    Google Scholar 

  • Faye-Lund H (1985) The neocortical projection to the inferior colliculus in the albino rat. Anat Embryol 173:53–70

    Google Scholar 

  • Friedrich B (1985) Die Cytoarchitektur des Geniculatum mediale der Ratte. Abstr Neurobiologentagung Göttingen: 181

  • Imig TJ, Morel A (1983) Organization of the thalamocortical auditory system in the cat. Ann Rev Neurosc 6:95–120

    Google Scholar 

  • Imig TJ, Morel A (1984) Topographic and cytoarchitectonic organization of thalmic neurons related to their targets in lowmiddle-, and high-frequency representations in cat auditory cortex. J Comp Neurol 227:511–539

    Google Scholar 

  • Imig TJ, Morel A (1985) Tonotopic organization in lateral part of posterior group of thalamic nuclei in the cat. J Neurophysiol 53:839–851

    Google Scholar 

  • Imig TJ, Morel A (1986) Organization of binaural interactions in the high frequency representation of the ventral nucleus of the cat's medial geniculate body. Neurosci [Abstr] 12:1272

    Google Scholar 

  • Jones EG (1985) The thalamus. Plenum Press, New York

    Google Scholar 

  • Krieg WJS (1946a) Connections of the cerebral cortex. I. The albino rat. A. Topography of the cortical areas. J Comp Neurol 84:221–275

    Google Scholar 

  • Krieg WJS (1946b) Connections of the cerebral cortex. I. The albino rat. B. Structure of the cortical areas. J Comp Neurol 84:277–323

    Google Scholar 

  • Krieg WJS (1947) Connections of the cerebral cortex. I. The albino rat. C. Extrinsic connections. J Comp Neurol 86:267–394

    Google Scholar 

  • Lashley KS (1941) Thalamo-cortical connections of the rat's brain. J Comp Neurol 75:67–121

    Google Scholar 

  • Le Doux JE, Ruggiero DA, Forest R, Stornetta R, Reis DJ (1987) Topographic organization of convergent projections to the thalamus from the inferior colliculus and spinal cord in the rat. J Comp Neurol 264:123–146

    Google Scholar 

  • Mesulam MM (1978) Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: A non-carcenogenic blue reaction-product with superior sensitivity for visualizing neural afferents and efferents. J Histochem Cytochem 26:106–117

    Google Scholar 

  • Mesulam MM (1982) Tracing neural connections with horseradish peroxidase. John Wiley and Sons, Chichester New York Brisbane Toronto Singapore

    Google Scholar 

  • Merzenich MM, Roth GL, Andersen RA, Knight PL, Colwell SA (1977) Some basic features of organization of the central auditory nervous system. In: Evans EF, Wilson JP (eds): Psychophysics and physiology of hearing. Academic Press, London, pp 485–497

    Google Scholar 

  • Merzenich MM, Colwell SA, Andersen RA (1982) Auditory forebrain organization, thalamocortical and corticothalamic connections in the cat. In: Woolsey CN (ed): Cortical sensory organization, vIII, Multiple auditory areas. Humana Press, Clifton, NJ, pp 43–57

    Google Scholar 

  • Michels M (1981) Periphere und zentrale Antworten im Hörsystem der Ratte bei Reintonreizung. Diplomarbeit, Univ Marburg

  • Morel A, Imig TJ (1987) Thalamic projections to fields A, AI, P and VP in the cat auditory cortex. J Comp Neurol 265:119–144

    Google Scholar 

  • Morest DK (1964) The neuronal architecture of the medial geniculate body of the cat. J Anat (Lond) 98:611–630

    Google Scholar 

  • Morest DK (1965) The laminar structure of the medial geniculate body of the cat. J Anat (Lond) 99:143–160

    Google Scholar 

  • Niimi K, Matsuoka H (1979) Thalamocortical organization of the auditory system in the cat studied by retrograde axonal transport of HRP. Adv Anat Embryol Cell Biol 57:1–56

    Google Scholar 

  • Oliver DL, Hall WC (1978a) The medial geniculate body of the tree shrew, Tupaia glis. I. Cytoarchitecture and midbrain connections. J Comp Neurol 182:423–458

    Google Scholar 

  • Oliver DL, Hall WC (1978b) The medial geniculate body of the tree shrew, Tupaia glis. II. Connections with the neocortex. J Comp Neurol 182:459–494

    Google Scholar 

  • Olmos JS de, Heimer L (1977) Mapping of collateral projection with the HRP method. Neurosci Lett 6:107–114

    Google Scholar 

  • Patterson HA (1977) An anterograde degeneration and retrograde axonal transport study of the cortical projections of the rat medial geniculate body. Ph.D, Boston Univ School of Education

  • Reale RA, Imig TJ (1980) Tonotopic organization in auditory cortex of the cat. J Comp Neurol 192:265–291

    Google Scholar 

  • Redies H (1987) Tonotope Strukturen im auditorischen Cortex des Meerschweinchens. Dissertation, Univ Göttingen

  • Romeis B (1968) Mikroskopische Technik. 16th edn, Oldenbourg, München

    Google Scholar 

  • Steines Wm, Kimura H, Fibiger HC, McGeer EG (1980) Peroxidase-labeled lectin as a neuroanatomical tracer: evaluation in a CNS pathway. Brain Res 197:485–490

    Google Scholar 

  • Syka J, Druga R (1981) Functional organization of the auditory cortico-collicular pathway in the rat. Physiol Bohemoslov 30:459

    Google Scholar 

  • Vaughan DW, Foundas S (1982) Synaptic proliferation in the auditory cortex of the young adult rat following callosal lesions. J Neurocytol 11:29–51

    Google Scholar 

  • Waller WH (1934) Topographical relations of cortical lesions to thalamic nuclei in the albino rat. J Comp Neurol 60:237–269

    Google Scholar 

  • Webster WR (1985) Auditory system. In: Paxinos G (ed) The rat nervous system, vol 2. Hindbrain and spinal cord. Academic Press, Sydney

    Google Scholar 

  • Winer JA, Larue DT (1987) Patterns of reciprocity in auditory thalamocortical and corticothalamic connections: Study with horseradish peroxidase and autoradiographic methods in the rat medial geniculate body. J Comp Neurol 257:282–315

    Google Scholar 

  • Zilles K (1985) The cortex of the rat. Spinger, Berlin Heidelberg New York Tokyo

    Google Scholar 

  • Zilles K, Wree A (1985) Areal and laminar structure of the rat cortex. In: Paxinos G (ed) The rat nervous system, vol 1. Academic Press, Sydney

    Google Scholar 

Download references

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  1. Department of Animal Physiology, University of Tübingen, Auf der Morgenstelle 28, D-7400, Tübingen, Federal Republic of Germany

    Marlies Scheel

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  1. Marlies Scheel
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Scheel, M. Topographic organization of the auditory thalamocortical system in the albino rat. Anat Embryol 179, 181–190 (1988). https://doi.org/10.1007/BF00304700

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