Summary
An esterase located within lipid droplets of mouse liver and kidney is demonstrated by electron microscopy employing acetic acid and butyric acid esters of 8-hydroxiquinoline. This enzyme accounts for a considerable amount of the esterase activity in the glutaraldehyde fixed liver and is identical with the droplet esterase found chiefly in the central area of the lobule. Possibly it is different from the “droplet” esterase described by other authors. In the kidney there is less of this lipid droplet esterase. Some aspects regarding its origin and its biological significance concerning lipid metabolism are discussed.
Zusammenfassung
Mit den Essig- und Buttersäureestern von 8-Hydroxichinolin wurde eine Lipidtropfenesterase in der Leber und der Niere der Maus elektronenmikroskopisch dargestellt. Sie stellt in der fixierten Leber einen beträchtlichen Anteil der Esteraseaktivität dar und ist identisch mit der lichtmikroskopisch vorzugsweise im Läppchenzentrum tropfenförmig erscheinenden Esterase. Möglicherweise ist sie mit der „tropfigen” Esterase anderer Autoren nicht identisch. In der Niere ist die Lipidtropfenesterase weniger reichlich vertreten. Es werden Anhaltspunkte zur Herkunft der Lipidtropfenesterase gegeben. Die mögliche Bedeutung für den Lipidstoffwechsel wird diskutiert.
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Madreiter, H., v. Deimling, O. Esterase. Histochemie 36, 139–148 (1973). https://doi.org/10.1007/BF00304389
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DOI: https://doi.org/10.1007/BF00304389