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Magnetic resonance imaging before chemonucleolysis for lumbar disc prolapse

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Summary

Chemonucleolysis is an established non-operative treatment of a prolapsed symptomatic lumbar disc. It was introduced as a form of treatment in the early 1960s by Smith [18]. One of the main causes of failure is the difficulty in pre-operative assessment of a contained disc prolapse. Reducing failure rates is very important for the morale of surgeon and patient alike. We investigated 58 patients with magnetic resonance imaging (MRI) to select those with a contained protrusion prior to chemonucleolysis. Per-operative discography confirmed contained protrusion in 96.5% (56/58) of cases, increasing the specificity of selection. At 6 months post chemonucleolysis 86% of our patients were asymptomatic. We would commend MRI as the investigation method of choice prior to chemonucleolysis for a prolapsed symptomatic lumbar disc, thus avoiding separate diagnostic discography, thereby reducing inconvenience to the patient and wastage of prepared chymopapain.

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Gosal, H.S., Harrison, D.J. Magnetic resonance imaging before chemonucleolysis for lumbar disc prolapse. Eur Spine J 4, 206–209 (1995). https://doi.org/10.1007/BF00303411

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  • DOI: https://doi.org/10.1007/BF00303411

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