Abstract
A high incidence of congenital malformations associated with Wilms' tumor has been recognized lately. Aniridia, hemihypertrophy, and urinary tract anomalies are among the most frequently reported. Anomalies of the central nervous system associated with Wilms' tumor are rare. We report a previously healthy 4-year-old girl who presented with an intracranial hemorrhage secondary to a ruptured arteriovenous malformation. A routine abdominal examination revealed a large right-sided Wilms' tumor. The question generated by the coexistence of these two uncommon disorders in one individual is whether there is a genetic or other relationship between them, or whether this is merely a coincidental occurrence. The question at this point is unanswered and must await demonstration of additional, similar cases.
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Lemerle J, Tournade M, Marchant RG, Flamant R, Sarrazin D, Flamant M, Lemerle M, Juntd S, Zucker J, Schweisguth O (1976) Wilms' tumor: natural history and prognostic factors. A retrospective study of 248 cases treated at the Institute Gustave-Roussy 1952–1967. Cancer 37:2557–2566
Marosvari I, Kontor E, Kallay K (1972) Renin secreting Wilms' tumor. Lancet I:1180
Miller RW, Fraumeni JF, Manning MD (1964) Association of Wilms' tumor with aniridia, hemihypertrophy and other congenital malformations. N Engl J Med 270:922–927
Pendergrass TW (1976) Congenital anomalies in children with Wilms' tumor. Cancer 37:403–409
Sukarochan K, Tolentino W, Kiesewetter W (1972) Wilms' tumor and hypertension. J Pediatr Surg 7:573–578
Takamiya Y, Toya S, Otani M, Inoue H, Okui S, Takenaka N (1985) Wilms' tumor with intracranial metastases presenting with intracranial hemorrhage. Child's Nerv Sys 1:291–294
Watanabe Y, Todani T, Fujii T, Toki A, Uemura S, Koike Y (1985) Wilms' tumor associated with moyamoya disease: case report. Z Kinderchir 40:114–116
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Rosenn, G., Maytal, J. & Lantos, G. Association of Wilms' tumor and intracranial hemorrhage due to arteriovenous malformation. Child's Nerv Syst 10, 135–137 (1994). https://doi.org/10.1007/BF00302779
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DOI: https://doi.org/10.1007/BF00302779