Abstract
Fourteen hydrocephalic children were studied who were between the ages of 6 months and 14 years. Regional cerebral blood flow (rCBF) was measured by the 133Xe intravenous injection method after ventriculoperitonal shunting. There was a negative correlation between slow flow and preoperative ventricular size (r=-0.718, P<0.02), but there was no correlation between fast flow and preoperative ventricular size. There was also no correlation between rCBF and postoperative ventricular size. Postoperative IQ or development quotient showed a positive correlation with slow flow (r=0.813, P<0.01), but not with fast flow. It is suggested that in hydrocephalic children there is impairment of white-matter communicating fibres and secondary reduction in higher intellectual activity.
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Mabe, H., Suzuki, K. & Nagai, H. Cerebral blood flow after ventriculoperitoneal shunt in children with hydrocephalus. Child's Nerv Syst 6, 388–391 (1990). https://doi.org/10.1007/BF00302224
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DOI: https://doi.org/10.1007/BF00302224