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Cytology of the nasal mucosa

A comparative study between a replica-method and a smear-method
  • N. Mygind
  • J. Thomsen
Article

Summary

Cytological examination of the nasal mucosa has been performed in normal persons and in patients with perennial rhinitis. A replica-method and a smear-method have been evaluated. By blinded examination of the slides no difference could be demonstrated between the two groups with the replica-method, whereas it was possible in the nasal smears to show that patients with perennial rhinitis had a significant increase of the number of epithelial cells, eosinophilic leucocytes and mast cells. It is concluded that the smear-method is the most suitable for cytological examination of the nasal mucosa.

Keywords

Public Health Epithelial Cell Mast Cell Rhinitis Mast 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Bei Normalpersonen und bei Patienten mit Dauerschnupfen wurde die Nasenschleimhaut cytologisch mit der Abdruck- und der Ausstrichmethode untersucht. Bei Inspektion der Präparate ohne Kenntnis des angewandten Verfahrens konnten bei der Abdruckmethode keine Unterschiede zwischen beiden Gruppen festgestellt werden, dagegen zeigten die Ausstriche bei Patienten mit dauernder Rhinitis eine deutliche Vermehrung der Epithelzellen, der eosinophilen Leukocyten und der Mastzellen. Die Ergebnisse zeigen, daß die Ausstrichmethode das geeignete Verfahren zur cytologischen Untersuchung der Nasenschleimhaut darstellt.

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References

  1. Andersen, H. C.: Studies on the clinical aspects, etiology and pathogenesis of nasal polyps and hyperplastic sinusitis with speciel reference to eosinophilia. Thesis. Copenhagen: Thanning & Appel 1943.Google Scholar
  2. Bryan, W. T. K., Bryan, M. P.: Significance of mast cells in nasal secretions. Trans. Amer. Acad. Ophthal. Otolaryng. 63, 613–627 (1959).Google Scholar
  3. Hansel, F. K.: Clinical allergy, p. 408. St. Louis: Mosby 1953.Google Scholar
  4. Johnson, K. J.: Mast cells and eosinophils in food and inhalent allergy. Ann. Allergy 20, 657–660 (1962).Google Scholar
  5. Mygind, N. : Eosinophihc leucocytes in blood and in nasal smears in patients with diseases in the nasal mucosa 1. Acts allerg. (Kbh.) (in press).Google Scholar
  6. Schou, J. W., Anthonisen, P., Riis, P.: Cytological examination of mucosal secretion in nose, throat, oral cavity and oesophagus by a replica method. Acta oto-laryng. (Stockh.) 56, 563–570 (1963).Google Scholar

Copyright information

© Springer-Verlag 1973

Authors and Affiliations

  • N. Mygind
    • 1
  • J. Thomsen
    • 1
  1. 1.Department and Medical Out-patients' Clinic, Division for Allergic DiseasesOtopathological Laboratory, University ENTRigshospitalet, Copenhagen ØDenmark

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