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Hexosamin in den Innenohrflüssigkeiten bei Mensch und Meerschweinchen

Hexosamine in the inner ear fluids of man and guinea-pig

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Summary

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  1. 1.

    The N-acetylglucosamine as the most important component of the acid mucopolysaccharides (Glycosaminglycans) was determined in perilymph and endolymph in human and in guinea-pig.

  2. 2.

    For comparison, the N-acetylglucosamine was determined in blood, amnion, spinal and body fluid.

  3. 3.

    The low concentration of hexosamine in perilymph and endolymph makes one to consider that the acid-mucopolysaccharide has little effect on the chemical-physical properties in the inner ear fluids. A conclusion on the component of the mucopolysaccharide of the inner ear tissues and the membranous properties is not possible.

Zusammenfassung

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  1. 1.

    N-acetylglucosamin als wichtigster Bestandteil der sauren Mucopolysaccharide (Glykosaminglycans) wurde in der Perilymphe beim Menschen und in der Peri- und Endolymphe beim Meerschweinchen bestimmt.

  2. 2.

    Zum Vergleich wurde N-acetylglucosamin im Blut, Liquor, Frucht- und Gewebswasser bestimmt.

  3. 3.

    Der niedrige Hexosamingehalt in der Peri- und Endolymphe laßt vermuten, daß saure Mucopolysaccharide in den Innenohrflüssigkeiten mengenmäßig unbedeutend sind. Ihr Einfluß auf die chemisch-physikalischen Eigenschaften, insbesondere der Endolymphe, kann daher nur klein sein. Ein Rückschluß auf den Mucopolysaccharidgehalt des Innenohrgewebes und dessen Membraneigenschaften ist allerdings nicht möglich.

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Schnieder, E.A., Schindler, K. Hexosamin in den Innenohrflüssigkeiten bei Mensch und Meerschweinchen. Arch. Klin. Exp. Ohr.-, Nas.- U. Kehlk. Heilk. 192, 20–31 (1968). https://doi.org/10.1007/BF00301489

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