Abstract
The anti-inflammatory effects of recombinant human manganese superoxide dismutase on adjuvant arthritis was investigated. Local application of this manganese superoxide dismutase given every 2 days not only significantly reduced foot swelling but also retarded radiological bone destruction in adjuvant arthritis. Copper zinc superoxide dismutase had little effect on foot swelling.
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Shingu, M., Takahashi, S., Ito, M. et al. Anti-inflammatory effects of recombinant human manganese superoxide dismutase on adjuvant arthritis in rats. Rheumatol Int 14, 77–81 (1994). https://doi.org/10.1007/BF00300251
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DOI: https://doi.org/10.1007/BF00300251