Calcified Tissue International

, Volume 57, Issue 1, pp 69–73

Changes in mean trabecular orientation in the medial condyle of the proximal tibia in osteoarthritis

  • L. Kamibayashi
  • U. P. Wyss
  • T. D. V. Cooke
  • B. Zee
Orthopedic Surgical Forum

DOI: 10.1007/BF00299000

Cite this article as:
Kamibayashi, L., Wyss, U.P., Cooke, T.D.V. et al. Calcif Tissue Int (1995) 57: 69. doi:10.1007/BF00299000


In osteoarthritis of the knee, degenerative changes occur in the articular cartilage and underlying subchondral bone, particularly of the medial tibial condyle. Cancellous bone sclerosis that accompanies osteoarthritis is not only the result of an increase in bone volume fraction but also a change in trabecular structure. In a comparison with agematched controls (n=4), osteoarthritis (n=11) demonstrated a significant (P≤0.05) increase in bone volume fraction and trabecular thickness. Overal trabecular orientation in the osteoarthritic group was more vertical or perpendicular to the articular surface than the control group (P≤0.05) especially in the trabeculae of the cancellous bone layer closest to the articular surface. These alterations in trabecular bone structure could have significant consequences for the mechanical properties of osteoarthritic bone.

Key words

Trabecular orientation Osteoarthritis Medial tibial condyle Subchondral sclerosis 

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • L. Kamibayashi
    • 1
  • U. P. Wyss
    • 2
  • T. D. V. Cooke
    • 3
  • B. Zee
    • 4
  1. 1.Department of Anatomy and Cell BiologyQueen's UniversityKingstonCanada
  2. 2.Clinical Mechanics GroupQueen's UniversityKingstonCanada
  3. 3.King Faisal Specialist HospitalRiyadhKingdom of Saudi Arabia
  4. 4.Clinical Trials GroupQueen's UniversityKingstonCanada

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