Skip to main content

Advertisement

Log in

Management of corticosteroid-induced osteoporosis: A clinician's perspective

  • Editorials
  • Published:
Calcified Tissue International Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Cushing H (1932) The basophil adenomas of the pituitary body and their clinical manifestations (pituitary basophilism). Bull Johns Hopkins Hosp 1:137–192

    Google Scholar 

  2. Jowsey J, Riggs BL (1970) Bone formation in hypercortisolism. Acta Endocrinol 63:21–28

    Google Scholar 

  3. Peck WA, Brant J, Miller I (1967) Hydrocortisone induced inhibition of protein synthesis and uridine incorporation in in vitro. Proc Natl Acad Sci 57:1599–1606

    Google Scholar 

  4. Klein RG, Arnaud SB, Gallagher JC, et al (1977) Intestinal calcium absorption in exogenous hypercortisonism: role of 25-hydroxyvitamin D and corticosteroid dose. J Clin Invest 60:253–259

    Google Scholar 

  5. Suzuki Y, Ichikawa Y, Saito E, Homma M (1983) Importance of increased urinary calcium excretion in the development of secondary hyperparathyroidism of patients under glucocorticoid therapy. Metabolism 32:151–156

    Google Scholar 

  6. Als OS, Gotfredsen A, Christiansen C (1985) The effect of glucocorticoids on bone mass in rheumatoid arthritis patients: influence of menopausal state. Arthritis Rheum 28:369–375

    Google Scholar 

  7. Hahn TJ (1978) Corticosteroid induced osteopenia. Arch Intern Med 138:882–885

    Google Scholar 

  8. Sambrook P, Birmingham J, Kempler S, Eberl S, Pocock N, Yeates M, Eisman J (1990) Corticosteroid effects on proximal femur bone loss. J Bone Miner Res 5:1211–1216

    Google Scholar 

  9. Lo Cascio V, Bonucci E, Ballanti P, Adami S, Tartarotti D, Guarrera G, DellaRocca C. Glucocorticoid osteoporosis: a longitudinal study

  10. Rickers H, Deding A, Christiansen C, Rodbro P (1984) Mineral loss in cortical and trabecular bone during high dose prednisone treatment. Calcif Tissue Int 36:269–273

    Google Scholar 

  11. Fantini F, Beltrametti P, Gallazzi M, Gattinera M, Gerloni V, Murelli M, Parrini M (1990) Evaluation of bone mineral loss due to steroids by dual-photon absorptiometry in chronically ill rheumatic children (abstract 648) 3rd Int Symp Osteoporosis, 1990

  12. Brandli D, Goldenhersh M, Hahn T, Greenwald M, Golde G, Silverman SL (1991) Growth hormone treatment of glucocorticoid induced osteoporosis. Clin Res 39:115a

    Google Scholar 

  13. Mazess RB (1990) Bone densitometry for clinical diagnosis and monitoring. In: Osteoporosis: physiological basis, assessment, and treatment, A Steinbock Symposium. Elsevier, New York, p. 77

    Google Scholar 

  14. Laan RJFM, van Riel PLCM, Bujis W, van Erning LJThO, Lemmens JAM, Corstens F, van de Putte LBA (1990) The diaphyseal to metaphyseal bone density (D/M ratio) does not identify patients with low dose prednisone associated osteopenia (abstract 618) 3rd Int Symp Osteoporosis, 1990

  15. Reid IR, Heap SW (1990) Determinants of vertebral mineral density in patients receiving long term glucocorticoid therapy. Arch Intern Med 150:2544–2548

    Google Scholar 

  16. Dykman TR, Gluck OS, Murphy WA, Hahn TJ, Hahn BH (1985) Evaluation of factors associated with glucocorticoid induced osteopenia in patients with rheumatic diseases. Arthritis Rheum 28:361–368

    Google Scholar 

  17. Gluck OS, Murphy WA, Hahn TJ, Hahn BH (1981) Bone loss in adults receiving alternate day glucocorticoid therapy: a comparison with daily therapy. Arthritis Rheum 24:892–898

    Google Scholar 

  18. Silverman SL, Brandli D, Greenwald M, Golde G (1989) Long term corticosteroid therapy is not always associated with low bone mineral density (abstract 465) J Bone Miner Res 4(suppl 1):s324

    Google Scholar 

  19. Dewan NA, Gallagher JC, Meyers P (1990) Bone density in corticosteroid treated patients with chronic lung diseases (abstract 417) J Bone Miner Res 5(suppl 2):s178

    Google Scholar 

  20. Laan RJFM, van Riel PLCM, Bujis W, van Erning LJThO, Lemmens JAM, Corstens F, van de Putte LBA (1990) Trabecular and cortical spinal mineral density in rheumatoid arthritis patients: effect of low dose prednisone therapy (abstract 620) 3rd Int Symp Osteoporosis

  21. Reid IR, Ibbertson HK (1986) Calcium supplements in the prevention of steroid induced osteoporosis. Am J Clin Nutr 44:287–290

    Google Scholar 

  22. La Croix AZ et al (1990) Thiazide diuretic agents and the incidence of hip fracture. N Engl J Med 322:286–290

    Google Scholar 

  23. Goulding A, Gold E (1988) Effects of chronic prednisoline treatment on bone resorption and bone composition in intact and ovariectomized rats. Endocrinology 122:482–487

    Google Scholar 

  24. Wong TK, Goodlin SJ, Korenman SG, Hahn TJ (1990) Bone mass response to testosterone replacement in hypogonadal men (abstract 1092) J Bone Miner Res 4(suppl 1) S390

  25. Hahn TJ, Halstead LR, Teitelbaum SL, Hahn BH (1979) Altered mineral metabolism in glucocorticoid induced osteopenia: effect of 25-hydroxyvitamin D administration. J Clin Invest 64:655–665

    Google Scholar 

  26. Dykman TR, Haralson JM, Gluck OS, Murphy WA, Teitelbaum SL, Hahn T, Hahn BH (1984) Effect of oral 1,25-dihydroxyvitamin D and calcium on glucocorticoid-induced osteopenia in patients with rheumatic diseases. Arthritis Rheum 27:1336–1343

    Google Scholar 

  27. Adachi JD, Bensen WG, Bell MJ, et al (1989) A randomized double blind placebo controlled trial of vitamin D and calcium in the prevention of corticosteroid induced bone loss (abstract 462) J Bone Miner Res 4(supp 1)

  28. Gennari C, Civitelli R, Agnusedei D. Corticosteroid induced osteoporosis (abstract 588) 3rd Int Symp Osteoporosis

  29. Messina OD, Barreira, Zanchetta JR, Bogado C, Sebastian O, Flores D, Riopedre M, Redondo G, Lazaro A, Maldonado Cocco JA (1990) Effect of low doses of deflazacort vs prednisone on bone mineral content in premenopausal rheumatoid arthritis. Arthritis Rheum

  30. Ringe JD, Welzel D (1987) Salmon calcitonin in the therapy of corticoid-induced osteoporosis. Eur J Clin Pharmacol 33:35–39

    Google Scholar 

  31. Rizzato G, Tosi G, Schiraldi G, Montemurro L, Zanni D, Sisti S (1988) Bone protection with salmon calcitonin in the long term steroid therapy of chronic sarcoidosis. Sarcoidosis 5:99–103

    Google Scholar 

  32. Bohning W, Ringe JD (1990) Intranasal calcitonin in steroid dependent chronic obstructive pulmonary disease (COPD) to prevent bone mass decrease: a one year controlled and randomized trial (abstract 597) 3rd Int Symp Osteoporosis

  33. DiMunno O, Pontrandolfo A, Occhipinti C, Pardini N, Prevention of corticosteroid induced bone loss with salmon calcitonin nasal spray (abstract 613) 3rd Int Symp Osteoporosis

  34. Montemurro L, Schiraldi G, Zanni D, Delpiano S, Fraioli P, Rizzato G. Two years treatment with calcitonin nasal spray: effective protection against corticosteroid induced osteoporosis (abstract 687) 3rd Int Symp Osteoporosis

  35. Reid IR, King AR, Alexander CJ, Ibbertson HK (1988) Prevention of steroid induced osteoporosis with (3-amino-1-hydroxypropylidene)-1, 1-bisphosphonate (APD). Lancet i:143–146

    Google Scholar 

  36. Reid IR, Heap SW, King AR, Ibbertson HK (1988) Two year follow-up of biphosphonate (APD) treatment in steroid osteoporosis. Lancet ii:1144

    Google Scholar 

  37. Watts NB, Harris ST, Genant HK, et al. (1990) Intermittent cyclical etidronate treatment of postmenopausal osteoporosis. N Engl J Med 323:73–79

    Google Scholar 

  38. Bayley TA, Harrison J, Basualdo J, Sturtridge, Josse R, Murray TM, Pritzker KPH, Vieth R, Goodwin S, Strauss A (1990) The long term treatment of steroid osteoporosis with fluoride. J Bone Miner Res 5:(suppl 1)s157-s161

    Google Scholar 

  39. Greenwald M, Silverman SL (1990) Steroid induced osteoporosis successfully treated with fluoride. J Bone Miner Res 5:(suppl 1)s230

  40. Riggs BL et al. (1990) Effect of fluoride treatment on fracture rate in postmenopausal women with osteoporosis. N Engl J Med 322:802–809

    Google Scholar 

  41. Adami S, Fossaluzza, Bertoldo F, Zamberlan N, Constantini M, LoCascio V. The therapy of corticosteroid induced osteoporosis with nandrolone decanoate (abstract 737) 3rd Int Symp Osteoporosis

  42. Balsan S, Steru D, Bourdeau A, Grimberg R, Lenoir G (1987) Effects of long term maintenance therapy with a new glucocorticoid, deflazacort, on mineral metabolism and statural growth. Calcif Tissue Int 40:303–309

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Silverman, S.L. Management of corticosteroid-induced osteoporosis: A clinician's perspective. Calcif Tissue Int 50, 101–103 (1992). https://doi.org/10.1007/BF00298781

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00298781

Navigation